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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 126: Aminotransferase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aspartate transaminase. [EC: 2.6.1.1]
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
  • Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.
  • This activity can be formed from EC 2.6.1.57 by controlled proteolysis.
 25 A0A072T324 A0A072T324 A0A072T324 A0A072T324 A0A076PTT0 A0A076PTT0 A0A076PTT0 A0A1H3IXP1 A0A1H3IXP1 A0A1H3IXP1
(15 more...)
Aspartate 4-decarboxylase. [EC: 4.1.1.12]
L-aspartate = L-alanine + CO(2).
  • Also catalyzes the decarboxylation of aminomalonate and the desulfination of 3-sulfino-L-alanine to sulfite and alanine.
  • Formerly EC 4.1.1.10.
 25 A0A072T324 A0A072T324 A0A072T324 A0A072T324 A0A076PTT0 A0A076PTT0 A0A076PTT0 A0A1H3IXP1 A0A1H3IXP1 A0A1H3IXP1
(15 more...)