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CATH Superfamily 3.40.640.10

Type I PLP-dependent aspartate aminotransferase-like (Major domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 125: Probable L-tyrosine/L-aspartate decarboxylase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aspartate 1-decarboxylase. [EC: 4.1.1.11]
L-aspartate = beta-alanine + CO(2).
    		 15 A0A0E3LV77 A0A0E3LV77 A0A0E3LV77 A0A0E3RG15 A0A0E3RG15 A0A0E3RG15 O58679 Q5JJ82 Q60358 Q8PXA5
    (5 more...)
    Tyrosine decarboxylase. [EC: 4.1.1.25]
    L-tyrosine = tyramine + CO(2).
    • The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine.
    		 11 A0A0E3LV77 A0A0E3LV77 A0A0E3LV77 A0A0E3RG15 A0A0E3RG15 A0A0E3RG15 Q60358 Q8PXA5 Q8PXA5 Q8PXA5
    (1 more...)
    Glutamate decarboxylase. [EC: 4.1.1.15]
    L-glutamate = 4-aminobutanoate + CO(2).
    • The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.
    		 1 O58679