The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Type I PLP-dependent aspartate aminotransferase-like (Major domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Ornithine aminotransferase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ornithine-oxo-acid transaminase activity GO:0004587
Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
18 P04181 (/TAS) P04181 (/TAS) P04181 (/TAS) P04181 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS)
(8 more)
Ornithine-oxo-acid transaminase activity GO:0004587
Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
7 P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) Q9FNK4 (/IMP)
Ornithine-oxo-acid transaminase activity GO:0004587
Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
7 Q54JP5 (/ISS) Q81TV3 (/ISS) Q81TV3 (/ISS) Q81TV3 (/ISS) Q81TV3 (/ISS) Q9FNK4 (/ISS) Q9VW26 (/ISS)
Ornithine-oxo-acid transaminase activity GO:0004587
Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
5 P38021 (/IDA) P38021 (/IDA) P38021 (/IDA) Q92413 (/IDA) Q9FNK4 (/IDA)
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity GO:0003992
Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
1 P04182 (/TAS)
Ornithine-oxo-acid transaminase activity GO:0004587
Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
1 Q92413 (/RCA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q9FNK4 (/IDA)

There are 33 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ornithine metabolic process GO:0006591
The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
15 P04182 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS) Q6LFH8 (/TAS)
(5 more)
Arginine catabolic process GO:0006527
The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
6 P07991 (/IC) P07991 (/IC) P07991 (/IC) P07991 (/IC) P07991 (/IC) P07991 (/IC)
Ornithine metabolic process GO:0006591
The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
6 P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) P07991 (/IMP) P07991 (/IMP)
Arginine catabolic process GO:0006527
The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
4 Q81TV3 (/ISS) Q81TV3 (/ISS) Q81TV3 (/ISS) Q81TV3 (/ISS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
4 P04181 (/TAS) P04181 (/TAS) P04181 (/TAS) P04181 (/TAS)
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
4 P04181 (/TAS) P04181 (/TAS) P04181 (/TAS) P04181 (/TAS)
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
4 P04181 (/IDA) P04181 (/IDA) P04181 (/IDA) P04181 (/IDA)
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
4 P04182 (/ISS) P29758 (/ISS) P29758 (/ISS) Q3ZCF5 (/ISS)
Arginine metabolic process GO:0006525
The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
3 P38021 (/IDA) P38021 (/IDA) P38021 (/IDA)
Protein hexamerization GO:0034214
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
2 P29758 (/ISO) P29758 (/ISO)
Arginine metabolic process GO:0006525
The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
1 Q92413 (/RCA)
Proline biosynthetic process GO:0006561
The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
1 Q9FNK4 (/IDA)
Ornithine metabolic process GO:0006591
The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
1 Q54JP5 (/IC)
Ornithine metabolic process GO:0006591
The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
1 Q9VW26 (/ISS)
Ornithine catabolic process GO:0006593
The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
1 Q9FNK4 (/IDA)
Ornithine catabolic process GO:0006593
The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
1 Q9FNK4 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q10G56 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q10G56 (/IEP)
Response to flooding GO:0009413
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.
1 Q10G56 (/IEP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
1 Q10G56 (/IMP)
Plant-type hypersensitive response GO:0009626
The rapid, localized death of plant cells in response to invasion by a pathogen.
1 Q9FNK4 (/TAS)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 Q9FNK4 (/IDA)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 Q10G56 (/IEP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 Q10G56 (/IEP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q10G56 (/IEP)
Response to brassinosteroid GO:0009741
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
1 Q10G56 (/IEP)
Response to jasmonic acid GO:0009753
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
1 Q10G56 (/IEP)
Defense response to bacterium, incompatible interaction GO:0009816
A response of an organism to a bacterium that prevents the occurrence or spread of disease.
1 Q9FNK4 (/IEP)
Arginine catabolic process to proline via ornithine GO:0010121
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine.
1 Q9P7L5 (/IMP)
Arginine catabolic process to glutamate GO:0019544
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.
1 Q9FNK4 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 A0A1D8PL14 (/IDA)
Hyperosmotic salinity response GO:0042538
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
1 Q9FNK4 (/IDA)
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
1 Q9FNK4 (/IDA)

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 A0A140VJQ4 (/IDA) A0A140VJQ4 (/IDA) A0A140VJQ4 (/IDA) A0A140VJQ4 (/IDA) P04181 (/IDA) P04181 (/IDA) P04181 (/IDA) P04181 (/IDA) P04182 (/IDA) Q9FNK4 (/IDA)
(1 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
8 A0A140VJQ4 (/IDA) A0A140VJQ4 (/IDA) A0A140VJQ4 (/IDA) A0A140VJQ4 (/IDA) P04181 (/IDA) P04181 (/IDA) P04181 (/IDA) P04181 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) Q9P7L5 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) P07991 (/HDA) P07991 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 P07991 (/IDA) P07991 (/IDA) P07991 (/IDA) P07991 (/IDA) P07991 (/IDA) P07991 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 P04181 (/TAS) P04181 (/TAS) P04181 (/TAS) P04181 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
4 P04181 (/NAS) P04181 (/NAS) P04181 (/NAS) P04181 (/NAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
4 P04181 (/TAS) P04181 (/TAS) P04181 (/TAS) P04181 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P29758 (/ISO) P29758 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P29758 (/ISO) P29758 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P29758 (/HDA) P29758 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P29758 (/ISO) P29758 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P04182 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q9VW26 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9P7L5 (/HDA)
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