The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6: Putative n-alpha-acetyltransferase 50

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptide alpha-N-acetyltransferase activity GO:0004596
Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Peptidyl-lysine acetyltransferase activity GO:0052858
Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Peptide alpha-N-acetyltransferase activity GO:0004596
Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.
32 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(22 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
32 Q6PGB6 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI) Q9GZZ1 (/IPI)
(22 more)
Peptide alpha-N-acetyltransferase activity GO:0004596
Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.
31 Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP)
(21 more)
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
31 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(21 more)
Peptidyl-lysine acetyltransferase activity GO:0052858
Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.
31 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(21 more)
N-acetyltransferase activity GO:0008080
Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.
5 Q38BT1 (/ISM) Q38BT1 (/ISM) Q38BT1 (/ISM) Q38BT1 (/ISM) Q9NHD5 (/ISM)
Peptide alpha-N-acetyltransferase activity GO:0004596
Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.
1 Q6PGB6 (/ISO)
N-acetyltransferase activity GO:0008080
Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.
1 Q9NHD5 (/ISS)
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
1 Q6PGB6 (/ISO)
Peptidyl-lysine acetyltransferase activity GO:0052858
Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.
1 Q6PGB6 (/ISO)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Establishment of mitotic sister chromatid cohesion GO:0034087
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Mitotic sister chromatid cohesion, centromeric GO:0071962
The cell cycle process in which centromeres of sister chromatids are joined during mitosis.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
32 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(22 more)
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
32 Q6PGB6 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS) Q9GZZ1 (/TAS)
(22 more)
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
31 Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP) Q9GZZ1 (/IMP)
(21 more)
Establishment of mitotic sister chromatid cohesion GO:0034087
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
31 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(21 more)
Mitotic sister chromatid cohesion, centromeric GO:0071962
The cell cycle process in which centromeres of sister chromatids are joined during mitosis.
31 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(21 more)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
1 Q9NHD5 (/IMP)
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1 Q6DBY2 (/IMP)
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
1 Q6PGB6 (/ISO)
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
1 Q9NHD5 (/IMP)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
1 Q9NHD5 (/IMP)
Establishment of mitotic sister chromatid cohesion GO:0034087
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
1 Q6PGB6 (/ISO)
Mitotic sister chromatid cohesion, centromeric GO:0071962
The cell cycle process in which centromeres of sister chromatids are joined during mitosis.
1 Q6PGB6 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
66 Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS) Q0IIJ0 (/ISS)
(56 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
32 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(22 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
32 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(22 more)
NatA complex GO:0031415
A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.
32 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(22 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
31 Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA) Q9GZZ1 (/IDA)
(21 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
31 Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA) Q9GZZ1 (/HDA)
(21 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q6PGB6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q6PGB6 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q6PGB6 (/ISO)
Protein acetyltransferase complex GO:0031248
A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule.
1 Q9NHD5 (/IPI)
NatA complex GO:0031415
A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.
1 Q6PGB6 (/ISO)
CATH-Gene3D is a Global Biodata Core Resource Learn more...