The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 21: Serotonin N-acetyltransferase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Aralkylamine N-acetyltransferase activity GO:0004059
Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
|
39 |
A0A087R2G5 (/ISS)
A0A091F660 (/ISS)
A0A091FPZ2 (/ISS)
A0A091ID94 (/ISS)
A0A091J5R9 (/ISS)
A0A091ML76 (/ISS)
A0A091UPN6 (/ISS)
A0A093GF51 (/ISS)
A0A093RHW9 (/ISS)
A0A286XWC7 (/ISS)
(29 more) |
|
Aralkylamine N-acetyltransferase activity GO:0004059
Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
|
6 | P79774 (/IDA) Q16613 (/IDA) Q16613 (/IDA) Q29495 (/IDA) Q29495 (/IDA) Q64666 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q16613 (/IPI) Q16613 (/IPI) Q29495 (/IPI) Q29495 (/IPI) |
|
Aralkylamine N-acetyltransferase activity GO:0004059
Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
|
3 | Q16613 (/TAS) Q16613 (/TAS) Q64666 (/TAS) |
|
Acetyltransferase activity GO:0016407
Catalysis of the transfer of an acetyl group to an acceptor molecule.
|
3 | Q6PCA1 (/IDA) Q6V7J8 (/IDA) Q9PVD7 (/IDA) |
|
Aralkylamine N-acetyltransferase activity GO:0004059
Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Aralkylamine N-acetyltransferase activity GO:0004059
Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
|
2 | Q16613 (/NAS) Q16613 (/NAS) |
|
Arylamine N-acetyltransferase activity GO:0004060
Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
|
2 | O88816 (/IDA) O88816 (/IDA) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q64666 (/IDA) |
There are 44 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
|
27 |
A0A286XWC7 (/ISS)
C1KBE4 (/ISS)
D2HD68 (/ISS)
F7AXK9 (/ISS)
F7IQE1 (/ISS)
G1QPW1 (/ISS)
G1T7L2 (/ISS)
G3HTY1 (/ISS)
G3RHH1 (/ISS)
G5AQU7 (/ISS)
(17 more) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
27 |
A0A286XWC7 (/ISS)
C1KBE4 (/ISS)
D2HD68 (/ISS)
F7AXK9 (/ISS)
F7IQE1 (/ISS)
G1QPW1 (/ISS)
G1T7L2 (/ISS)
G3HTY1 (/ISS)
G3RHH1 (/ISS)
G5AQU7 (/ISS)
(17 more) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
26 |
A0A286XWC7 (/ISS)
C1KBE4 (/ISS)
D2HD68 (/ISS)
F7AXK9 (/ISS)
F7IQE1 (/ISS)
G1QPW1 (/ISS)
G1T7L2 (/ISS)
G3HTY1 (/ISS)
G3RHH1 (/ISS)
G5AQU7 (/ISS)
(16 more) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
25 |
A0A286XWC7 (/ISS)
C1KBE4 (/ISS)
D2HD68 (/ISS)
F7AXK9 (/ISS)
F7IQE1 (/ISS)
G1QPW1 (/ISS)
G1T7L2 (/ISS)
G3HTY1 (/ISS)
G3RHH1 (/ISS)
G5AQU7 (/ISS)
(15 more) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
4 | Q16613 (/IDA) Q16613 (/IDA) Q29495 (/IDA) Q29495 (/IDA) |
|
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
|
2 | Q16613 (/IDA) Q16613 (/IDA) |
|
N-terminal protein amino acid acetylation GO:0006474
The acetylation of the N-terminal amino acid of proteins.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | Q6PCA1 (/IDA) Q9PVD7 (/IDA) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | Q6PCA1 (/IGI) Q9PVD7 (/IGI) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | Q16613 (/IMP) Q16613 (/IMP) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | Q16613 (/NAS) Q16613 (/NAS) |
|
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
2 | Q6PCA1 (/IDA) Q9PVD7 (/IDA) |
|
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
2 | Q6PCA1 (/IGI) Q9PVD7 (/IGI) |
|
Photoperiodism GO:0009648
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
|
2 | Q6PCA1 (/IEP) Q9PVD7 (/IEP) |
|
Photoperiodism GO:0009648
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
2 | Q16613 (/NAS) Q16613 (/NAS) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
2 | P79774 (/TAS) Q64666 (/TAS) |
|
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
2 | Q6PCA1 (/IMP) Q9PVD7 (/IMP) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Response to prostaglandin E GO:0034695
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Positive regulation of circadian sleep/wake cycle, sleep GO:0045938
Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
|
2 | Q6PCA1 (/IMP) Q9PVD7 (/IMP) |
|
Indolalkylamine biosynthetic process GO:0046219
The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
|
2 | Q16613 (/TAS) Q16613 (/TAS) |
|
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
2 | Q16613 (/IDA) Q16613 (/IDA) |
|
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q64666 (/IEP) |
|
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
1 | Q64666 (/IEP) |
|
Photoperiodism GO:0009648
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
|
1 | Q64666 (/IDA) |
|
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
1 | Q64666 (/IDA) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | Q64666 (/IDA) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | Q64666 (/IDA) |
|
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | Q64666 (/IEP) |
|
Response to prostaglandin E GO:0034695
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
|
1 | Q64666 (/IDA) |
|
Entrainment of circadian clock by photoperiod GO:0043153
The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).
|
1 | Q64666 (/TAS) |
|
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
|
1 | Q64666 (/IDA) |
|
Response to corticosterone GO:0051412
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
|
1 | Q64666 (/IEP) |
|
Response to cAMP GO:0051591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
|
1 | Q64666 (/IEP) |
|
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q64666 (/IEP) |
|
Cellular response to UV-A GO:0071492
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
|
1 | P79774 (/IDA) |
|
Response to peptide GO:1901652
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
|
1 | Q64666 (/IEP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
27 |
A0A286XWC7 (/ISS)
C1KBE4 (/ISS)
D2HD68 (/ISS)
F7AXK9 (/ISS)
F7IQE1 (/ISS)
G1QPW1 (/ISS)
G1T7L2 (/ISS)
G3HTY1 (/ISS)
G3RHH1 (/ISS)
G5AQU7 (/ISS)
(17 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | F1T0I5 (/IDA) F1T0I5 (/IDA) Q16613 (/IDA) Q16613 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q16613 (/TAS) Q16613 (/TAS) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | Q16613 (/IDA) Q16613 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | O88816 (/ISO) O88816 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q64666 (/IDA) |
