The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: cysteine-rich protein 2-binding protein-like

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q8CID0 (/IPI) Q8CID0 (/IPI) Q9H8E8 (/IPI)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
2 Q8CID0 (/ISO) Q8CID0 (/ISO)
Histone acetyltransferase activity GO:0004402
Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
1 Q9H8E8 (/IDA)
H4 histone acetyltransferase activity GO:0010485
Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
1 Q9VJ73 (/IDA)
LIM domain binding GO:0030274
Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
1 Q9H8E8 (/NAS)
H2A histone acetyltransferase activity GO:0043998
Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.
1 Q9VJ73 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
2 Q8CID0 (/IMP) Q8CID0 (/IMP)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
2 Q8CID0 (/IMP) Q8CID0 (/IMP)
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
2 Q8CID0 (/ISO) Q8CID0 (/ISO)
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
1 Q9VJ73 (/IDA)
Histone acetylation GO:0016573
The modification of a histone by the addition of an acetyl group.
1 Q9VJ73 (/IDA)
Intestinal stem cell homeostasis GO:0036335
Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells.
1 Q9VJ73 (/IMP)
Histone H3 acetylation GO:0043966
The modification of histone H3 by the addition of an acetyl group.
1 Q9H8E8 (/IDA)
Histone H4 acetylation GO:0043967
The modification of histone H4 by the addition of an acetyl group.
1 Q9VJ73 (/IDA)
Histone H2A acetylation GO:0043968
The modification of histone H2A by the addition of an acetyl group.
1 Q9VJ73 (/IDA)
Positive regulation of histone H4-K16 acetylation GO:2000620
Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation.
1 Q9VJ73 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ada2/Gcn5/Ada3 transcription activator complex GO:0005671
A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.
4 Q8CID0 (/IDA) Q8CID0 (/IDA) Q9H8E8 (/IDA) Q9VJ73 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8CID0 (/IDA) Q8CID0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8CID0 (/ISO) Q8CID0 (/ISO)
Ada2/Gcn5/Ada3 transcription activator complex GO:0005671
A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.
2 Q8CID0 (/ISO) Q8CID0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9H8E8 (/IPI)
Ada2/Gcn5/Ada3 transcription activator complex GO:0005671
A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.
1 Q9VJ73 (/IPI)
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