The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Zn peptidases

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53: glutaminyl-peptide cyclotransferase-like protein

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutaminyl-peptide cyclotransferase. [EC:]
L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH(3).
  • Involved in the formation of thyrotropin-releasing hormone and other biologically active peptides containing N-terminal pyroglutamyl residues.
  • The enzyme from papaya also acts on glutaminyl-tRNA.
22 A0A2K5XIN9 A0A2K5XIN9 A0A2K5XIN9 A0A2K5XIN9 F7E1J2 F7E1J2 F7E1J2 F7E1J2 G8F4B6 G8F4B6
(12 more...)