The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zn peptidases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 27: N-fatty-acyl-amino acid synthase/hydrolase PM20D1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Carboxypeptidase activity GO:0004180
Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.
1 P27614 (/IMP)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016811
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
1 Q8C165 (/IDA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Amide biosynthetic process GO:0043604
The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Cellular amide catabolic process GO:0043605
The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Cellular lipid metabolic process GO:0044255
The chemical reactions and pathways involving lipids, as carried out by individual cells.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Adaptive thermogenesis GO:1990845
The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Regulation of oxidative phosphorylation uncoupler activity GO:2000275
Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
2 Q6GTS8 (/IDA) Q8C165 (/IDA)
Amide biosynthetic process GO:0043604
The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
2 Q6GTS8 (/IDA) Q8C165 (/IDA)
Cellular amide catabolic process GO:0043605
The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
2 Q6GTS8 (/IDA) Q8C165 (/IDA)
Cellular lipid metabolic process GO:0044255
The chemical reactions and pathways involving lipids, as carried out by individual cells.
2 Q6GTS8 (/IDA) Q8C165 (/IDA)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
1 Q8C165 (/ISO)
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
1 P27614 (/IMP)
Protein catabolic process in the vacuole GO:0007039
The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
1 O13968 (/NAS)
Amide biosynthetic process GO:0043604
The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
1 Q8C165 (/ISO)
Cellular amide catabolic process GO:0043605
The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
1 Q8C165 (/ISO)
Cellular lipid metabolic process GO:0044255
The chemical reactions and pathways involving lipids, as carried out by individual cells.
1 Q8C165 (/ISO)
Proteolysis involved in cellular protein catabolic process GO:0051603
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
1 P27614 (/IMP)
Proteolysis involved in cellular protein catabolic process GO:0051603
The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
1 O13968 (/ISO)
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
1 Q8C165 (/IMP)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
1 Q6GTS8 (/IMP)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
1 Q8C165 (/ISO)
Adaptive thermogenesis GO:1990845
The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.
1 Q8C165 (/IMP)
Regulation of oxidative phosphorylation uncoupler activity GO:2000275
Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
1 Q8C165 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
6 Q08BB2 (/ISS) Q08BB2 (/ISS) Q08BT9 (/ISS) Q2T9M7 (/ISS) Q32LT9 (/ISS) Q5ZL18 (/ISS)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
2 O13968 (/HDA) P27614 (/HDA)
Fungal-type vacuole lumen GO:0000328
The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.
1 P27614 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q8C165 (/IDA)
Vacuolar lumen GO:0005775
The volume enclosed within the vacuolar membrane.
1 P27614 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q6GTS8 (/HDA)
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