The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Aldehyde Dehydrogenase; Chain A, domain 1
".
FunFam 5: Succinate-semialdehyde dehydrogenase I
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 22 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
37 |
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
(27 more) |
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
19 |
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
(9 more) |
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
12 |
P51649 (/ISS)
P51649 (/ISS)
P51650 (/ISS)
Q3MSM3 (/ISS)
Q3MSM4 (/ISS)
Q6A2H0 (/ISS)
Q6A2H1 (/ISS)
Q6A2H2 (/ISS)
Q8BWF0 (/ISS)
Q8BWF0 (/ISS)
(2 more) |
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
12 |
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
(2 more) |
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
|
12 |
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
(2 more) |
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
9 | P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) |
Glutarate-semialdehyde dehydrogenase (NAD+) activity GO:0047949
Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH.
|
7 | Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) |
Glutarate-semialdehyde dehydrogenase (NAD+) activity GO:0047949
Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH.
|
6 | Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) |
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
2 | P51649 (/TAS) P51649 (/TAS) |
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
2 | Q9US47 (/ISO) Q9UTM8 (/ISO) |
Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
|
2 | E1V7V8 (/IDA) E1V7V8 (/IDA) |
Carboxylic acid binding GO:0031406
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | P51649 (/IC) P51649 (/IC) |
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
2 | P51650 (/IDA) Q9SAK4 (/IDA) |
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Glutathione-disulfide reductase activity GO:0004362
Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.
|
1 | Q38AY7 (/ISA) |
Succinate-semialdehyde dehydrogenase (NAD+) activity GO:0004777
Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
|
1 | Q9SAK4 (/ISA) |
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
|
1 | Q9SAK4 (/IDA) |
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
1 | Q59T88 (/NAS) |
Succinate-semialdehyde dehydrogenase [NAD(P)+] activity GO:0009013
Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
|
1 | C8V6Q8 (/RCA) |
Carboxylic acid binding GO:0031406
Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
|
1 | P51650 (/IPI) |
There are 63 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
46 |
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
A0A1V4B8A9 (/ISS)
(36 more) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
25 |
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
P25526 (/IMP)
(15 more) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
15 |
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
(5 more) |
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
|
12 |
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
(2 more) |
Glutamate decarboxylation to succinate GO:0006540
The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
|
10 | P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) Q9SAK4 (/IMP) |
Glutamate decarboxylation to succinate GO:0006540
The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
|
9 | P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) P38067 (/IGI) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
9 | P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) P38067 (/IMP) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
8 | P51650 (/ISS) Q3MSM3 (/ISS) Q3MSM4 (/ISS) Q6A2H0 (/ISS) Q6A2H1 (/ISS) Q6A2H2 (/ISS) Q8BWF0 (/ISS) Q8BWF0 (/ISS) |
L-lysine catabolic process GO:0019477
The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.
|
7 | Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) Q88RC0 (/ISS) |
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
7 | Q3MSM3 (/ISS) Q3MSM4 (/ISS) Q6A2H0 (/ISS) Q6A2H1 (/ISS) Q6A2H2 (/ISS) Q8BWF0 (/ISS) Q8BWF0 (/ISS) |
L-lysine catabolic process GO:0019477
The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.
|
6 | Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) Q9I6M5 (/IDA) |
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
5 | Q3MSM3 (/ISS) Q3MSM4 (/ISS) Q6A2H0 (/ISS) Q6A2H1 (/ISS) Q6A2H2 (/ISS) |
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Acetate metabolic process GO:0006083
The chemical reactions and pathways involving acetate, the anion of acetic acid.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Acetate metabolic process GO:0006083
The chemical reactions and pathways involving acetate, the anion of acetic acid.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Succinate metabolic process GO:0006105
The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Succinate metabolic process GO:0006105
The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Succinate metabolic process GO:0006105
The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Glutamate metabolic process GO:0006536
The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Glutamine metabolic process GO:0006541
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Glutamine metabolic process GO:0006541
The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Glycerophospholipid metabolic process GO:0006650
The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Glucosylceramide metabolic process GO:0006678
The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Galactosylceramide metabolic process GO:0006681
The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Galactosylceramide metabolic process GO:0006681
The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
2 | P51649 (/IMP) P51649 (/IMP) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Gamma-aminobutyric acid metabolic process GO:0009448
The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Respiratory electron transport chain GO:0022904
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Respiratory electron transport chain GO:0022904
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Neurotransmitter catabolic process GO:0042135
The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Neurotransmitter catabolic process GO:0042135
The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Ectoine catabolic process GO:0042400
The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
|
2 | E1V7V8 (/IMP) E1V7V8 (/IMP) |
Short-chain fatty acid metabolic process GO:0046459
The chemical reactions and pathways involving fatty acids with a chain length of less than C6.
|
2 | Q8BWF0 (/IMP) Q8BWF0 (/IMP) |
Short-chain fatty acid metabolic process GO:0046459
The chemical reactions and pathways involving fatty acids with a chain length of less than C6.
|
2 | P51649 (/ISS) P51649 (/ISS) |
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
2 | P51649 (/IDA) P51649 (/IDA) |
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Succinate metabolic process GO:0006105
The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
|
1 | P51650 (/IDA) |
Glutamate catabolic process GO:0006538
The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.
|
1 | Q9UTM8 (/ISO) |
Glutamate decarboxylation to succinate GO:0006540
The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
|
1 | Q9SAK4 (/IDA) |
Glutamate decarboxylation to succinate GO:0006540
The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
|
1 | Q9US47 (/ISO) |
Glutamate decarboxylation to succinate GO:0006540
The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
|
1 | C8V6Q8 (/RCA) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
1 | P51650 (/TAS) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | Q9SAK4 (/IMP) |
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
1 | Q9SAK4 (/IEP) |
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
1 | Q9SAK4 (/IMP) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
1 | Q38AY7 (/ISA) |
Gamma-aminobutyric acid catabolic process GO:0009450
The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
|
1 | P51650 (/TAS) |
Adaxial/abaxial axis specification GO:0009943
The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
|
1 | Q9SAK4 (/IMP) |
Maintenance of shoot apical meristem identity GO:0010492
The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
|
1 | Q9SAK4 (/IMP) |
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
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1 | Q9SAK4 (/IMP) |
Cotyledon development GO:0048825
The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
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1 | Q9SAK4 (/IMP) |
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
|
1 | P51650 (/IDA) |
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
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1 | Q9SAK4 (/IMP) |
Response to salt GO:1902074
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
|
1 | Q9SAK4 (/IEP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
12 |
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
P25526 (/IDA)
(2 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) P38067 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
9 | P51649 (/IDA) P51649 (/IDA) P51650 (/IDA) Q8BWF0 (/IDA) Q8BWF0 (/IDA) Q9SAK4 (/IDA) X5D299 (/IDA) X5DQN2 (/IDA) X5DQN2 (/IDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | P51649 (/HDA) P51649 (/HDA) Q8BWF0 (/HDA) Q8BWF0 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | P51649 (/ISS) P51649 (/ISS) P51650 (/ISS) Q9VBP6 (/ISS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q8BWF0 (/ISO) Q8BWF0 (/ISO) |
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
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2 | P51649 (/TAS) P51649 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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2 | Q9US47 (/HDA) Q9UTM8 (/HDA) |
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
1 | Q9SAK4 (/IDA) |
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
|
1 | Q9SAK4 (/IDA) |
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
|
1 | Q9SAK4 (/IDA) |