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CATH Superfamily 3.40.605.10

Aldehyde Dehydrogenase; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Aldehyde dehydrogenase

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.3]
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
  • Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
  • Formerly EC 1.1.1.70.
 168 A0A0L8VJN5 A0A0L8VJN5 A0A0L8VJN5 A0A0L8VJN5 A0A0L8VJN5 A0A0L8VJN5 A0A0L8VJN5 A0A0L8VJN5 A0A164UMT7 A0A164UMT7
(158 more...)
Coniferyl-aldehyde dehydrogenase. [EC: 1.2.1.68]
Coniferyl aldehyde + H(2)O + NAD(P)(+) = ferulate + NAD(P)H.
  • Also oxidizes other aromatic aldehydes, but not aliphatic aldehydes.
 50 A0A0C7ATV9 A0A0C7ATV9 A0A0C7ATV9 A0A0C7ATV9 A0A0C7ATV9 A0A0C7ATV9 A0A0C7ATV9 A0A1F0IW89 A0A1F0IW89 A0A1F0IW89
(40 more...)
Aldehyde dehydrogenase (NAD(P)(+)). [EC: 1.2.1.5]
An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
    		 15 A0A024R5D8 A0A024R5D8 A3RF36 P11883 P30838 P43353 P43353 P47739 Q1JPA0 Q3TX25
    (5 more...)
    Beta-apo-4'-carotenal oxygenase. [EC: 1.2.1.82]
    4'-apo-beta,psi-caroten-4'-al + NAD(+) + H(2)O = neurosporaxanthin + NADH.
    • Neurosporaxanthin is responsible for the orange color of of Neurospora.
    		 4 Q1K615 Q1K615 Q870P2 Q870P2
    Benzaldehyde dehydrogenase (NADP(+)). [EC: 1.2.1.7]
    Benzaldehyde + NADP(+) + H(2)O = benzoate + NADPH.
      		 1 Q84DC3
      Benzaldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.28]
      Benzaldehyde + NAD(+) + H(2)O = benzoate + NADH.
        		 1 Q84DC3
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