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CATH Superfamily 3.40.605.10

Aldehyde Dehydrogenase; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: N-succinylglutamate 5-semialdehyde dehydrogenase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinylglutamate-semialdehyde dehydrogenase. [EC: 1.2.1.71]
N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H(2)O = N-succinyl-L- glutamate + NADH.
  • This is the fourth enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine.
  • This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA.
  • The five enzymes involved in this pathway are EC 2.3.1.109, EC 3.5.3.23, EC 2.6.1.11, EC 1.2.1.71 and EC 3.5.1.96.
 1389 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9 A0A026UED9
(1379 more...)
Succinate-semialdehyde dehydrogenase (NADP(+)). [EC: 1.2.1.79]
Succinate semialdehyde + NADP(+) + H(2)O = succinate + NADPH.
  • This enzyme participates in the degradation of glutamate and 4-aminobutyrate.
  • It is similar to EC 1.2.1.24 and EC 1.2.1.16 but is specific for NADP(+).
  • The enzyme from Escherichia coli is 20-fold more active with NADP(+) than NAD(+).
 73 A0A045JTD4 A0A045JTD4 A0A045JTD4 A0A045JTD4 A0A045JTD4 A0A045JTD4 A0A045JTD4 A0A045JTD4 A0A0H3LGA9 A0A0H3LGA9
(63 more...)
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)). [EC: 1.2.1.90]
D-glyceraldehyde 3-phosphate + NAD(P)(+) + H(2)O = 3-phospho-D-glycerate + NAD(P)H.
  • The enzyme is part of the modified Embden-Meyerhof-Parnas pathway of the archaeon Thermoproteus tenax (cf. EC 1.2.1.9).
 10 A0A0E3K5I1 A0A0E3K5I1 A0A0E3K5I1 D0KR08 D0KR08 D0KR08 O57693 Q97U30 Q97U30 Q97U30