CATH Superfamily 3.40.50.920
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 5: Pyruvate dehydrogenase E1 component
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
132 |
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
(122 more) |
|
Pyruvate dehydrogenase activity GO:0004738
Catalysis of the oxidative decarboxylation of pyruvate.
|
132 |
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
P0AFG8 (/IGI)
(122 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
132 |
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
(122 more) |
|
Thiamine pyrophosphate binding GO:0030976
Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
|
132 |
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
(122 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
132 |
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
P0AFG8 (/IPI)
(122 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
132 |
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
P0AFG8 (/IDA)
(122 more) |
|
Pyruvate dehydrogenase activity GO:0004738
Catalysis of the oxidative decarboxylation of pyruvate.
|
5 | Q47US5 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) |
|
Pyruvate dehydrogenase (acetyl-transferring) activity GO:0004739
Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.
|
5 | Q47US5 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acetyl-CoA biosynthetic process from pyruvate GO:0006086
The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
|
5 | Q47US5 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
132 |
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
(122 more) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
132 |
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
P0AFG8 (/HDA)
(122 more) |
|
Cytosolic pyruvate dehydrogenase complex GO:0045250
Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.
|
5 | Q47US5 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) Q9KPF4 (/ISS) |
