View in Gene3D

CATH Superfamily 3.40.50.920

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 10: Pyruvate ferredoxin oxidoreductase, alpha subunit

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pyruvate synthase. [EC: 1.2.7.1]
Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+).
  • The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.
  • This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.
  • For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7.
 37 A0A0A6N4P4 A0A0A6N4P4 A0A0A6N4P4 A0A0A6N4P4 A0A0A6N4P4 A0A0A6N4P4 A0A0F6AL76 A0A0F6AL76 A0A0F6AL76 A0A0F6AL76
(27 more...)
Oxalate oxidoreductase. [EC: 1.2.7.10]
Oxalate + oxidized ferredoxin = 2 CO(2) + reduced ferredoxin.
    		 4 A0A1J5NM87 A0A1J5NM87 Q2RI41 Q2RI41
    Phenylglyoxylate dehydrogenase (acylating). [EC: 1.2.1.58]
    Phenylglyoxylate + NAD(+) + CoA = benzoyl-S-CoA + CO(2) + NADH.
    • The enzyme from Azoarcus evansii is specific for phenylglyoxylate.
    • 2-oxoisovalerate is oxidized at 15% of the rate for phenylglyoxylate.
    • Also reduces viologen dyes.
    		 1 Q8L3B1