The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: FRE4p Ferric reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferric-chelate reductase activity GO:0000293
Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
12 P53746 (/ISA) Q08905 (/ISA) Q08905 (/ISA) Q08905 (/ISA) Q08908 (/ISA) Q08908 (/ISA) Q08908 (/ISA) Q08908 (/ISA) Q08908 (/ISA) Q08908 (/ISA)
(2 more)
Ferric-chelate reductase activity GO:0000293
Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
4 P53746 (/IGI) Q08905 (/IGI) Q08905 (/IGI) Q08905 (/IGI)
Ferric-chelate reductase activity GO:0000293
Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
2 P36033 (/IDA) P36033 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Siderophore transport GO:0015891
The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 P53746 (/IMP) Q08905 (/IMP) Q08905 (/IMP) Q08905 (/IMP)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
3 Q08905 (/IMP) Q08905 (/IMP) Q08905 (/IMP)
Iron ion transport GO:0006826
The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 P36033 (/IDA) P36033 (/IDA)
Copper ion import GO:0015677
The directed movement of copper ions into a cell or organelle.
2 P36033 (/IDA) P36033 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 Q08908 (/HDA) Q08908 (/HDA) Q08908 (/HDA) Q08908 (/HDA) Q08908 (/HDA) Q08908 (/HDA) Q08908 (/HDA) Q08908 (/HDA)
Fungal-type vacuole GO:0000324
A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
5 P36033 (/HDA) P36033 (/HDA) Q08905 (/HDA) Q08905 (/HDA) Q08905 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P36033 (/IDA) P36033 (/IDA) Q08905 (/IDA) Q08905 (/IDA) Q08905 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P53746 (/IMP)
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