The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 99: Aspartate-semialdehyde dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
44 P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI) P08390 (/IPI)
(34 more)
Aspartate-semialdehyde dehydrogenase activity GO:0004073
Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH.
10 P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) Q8VYI4 (/IDA) Q8VYI4 (/IDA)
Aspartate-semialdehyde dehydrogenase activity GO:0004073
Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH.
4 P23247 (/ISS) P23247 (/ISS) P23247 (/ISS) P23247 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lysine biosynthetic process via diaminopimelate GO:0009089
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
8 P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA)
Diaminopimelate biosynthetic process GO:0019877
The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
8 P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA) P9WNX5 (/IDA)
Methionine biosynthetic process GO:0009086
The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
4 P23247 (/ISS) P23247 (/ISS) P23247 (/ISS) P23247 (/ISS)
Threonine biosynthetic process GO:0009088
The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
4 P23247 (/ISS) P23247 (/ISS) P23247 (/ISS) P23247 (/ISS)
Lysine biosynthetic process via diaminopimelate GO:0009089
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
4 P23247 (/ISS) P23247 (/ISS) P23247 (/ISS) P23247 (/ISS)
Isoleucine biosynthetic process GO:0009097
The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
4 P23247 (/ISS) P23247 (/ISS) P23247 (/ISS) P23247 (/ISS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
36 P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA) P08390 (/IDA)
(26 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
8 P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA) P9WNX5 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8VYI4 (/IDA) Q8VYI4 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
2 Q8VYI4 (/IDA) Q8VYI4 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
2 Q8VYI4 (/IDA) Q8VYI4 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q8VYI4 (/IDA) Q8VYI4 (/IDA)