The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: calcium-activated potassium channel subunit alpha-...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 H7BRC9 (/IPI) H7BRM4 (/IPI) H7BRM5 (/IPI) H7BRM7 (/IPI) H8ESD6 (/IPI) H8ESD8 (/IPI) H8ESE2 (/IPI) H8ESE3 (/IPI) H8ESE4 (/IPI) H8ESE5 (/IPI)
(6 more)
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
14 H7BRC9 (/IDA) H7BRM4 (/IDA) H7BRM5 (/IDA) H7BRM7 (/IDA) H8ESD6 (/IDA) H8ESD8 (/IDA) H8ESE2 (/IDA) H8ESE3 (/IDA) H8ESE4 (/IDA) H8ESE5 (/IDA)
(4 more)
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
12 H7BRC9 (/IDA) H7BRM4 (/IDA) H7BRM5 (/IDA) H7BRM7 (/IDA) H8ESD6 (/IDA) H8ESD8 (/IDA) H8ESE2 (/IDA) H8ESE3 (/IDA) H8ESE4 (/IDA) H8ESE5 (/IDA)
(2 more)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
2 Q28204 (/ISA) Q28265 (/ISA)
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
2 Q28204 (/ISA) Q28265 (/ISA)
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2 Q28204 (/ISA) Q28265 (/ISA)
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
2 Q28204 (/ISA) Q28265 (/ISA)
Large conductance calcium-activated potassium channel activity GO:0060072
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
2 Q28204 (/ISA) Q28265 (/ISA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 Q12791 (/IDA)
Calcium-activated potassium channel activity GO:0015269
Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
1 Q03720 (/NAS)
Large conductance calcium-activated potassium channel activity GO:0060072
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
1 Q12791 (/IDA)
Large conductance calcium-activated potassium channel activity GO:0060072
Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
1 Q12791 (/IMP)

There are 56 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
13 H7BRC9 (/IDA) H7BRM4 (/IDA) H7BRM5 (/IDA) H7BRM7 (/IDA) H8ESD6 (/IDA) H8ESD8 (/IDA) H8ESE2 (/IDA) H8ESE3 (/IDA) H8ESE4 (/IDA) H8ESE5 (/IDA)
(3 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
12 H7BRC9 (/IMP) H7BRM4 (/IMP) H7BRM5 (/IMP) H7BRM7 (/IMP) H8ESD6 (/IMP) H8ESD8 (/IMP) H8ESE2 (/IMP) H8ESE3 (/IMP) H8ESE4 (/IMP) H8ESE5 (/IMP)
(2 more)
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
11 H7BRC9 (/IGI) H7BRM4 (/IGI) H7BRM5 (/IGI) H7BRM7 (/IGI) H8ESD6 (/IGI) H8ESD8 (/IGI) H8ESE2 (/IGI) H8ESE3 (/IGI) H8ESE4 (/IGI) H8ESE5 (/IGI)
(1 more)
Pharyngeal pumping GO:0043050
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
11 H7BRC9 (/IMP) H7BRM4 (/IMP) H7BRM5 (/IMP) H7BRM7 (/IMP) H8ESD6 (/IMP) H8ESD8 (/IMP) H8ESE2 (/IMP) H8ESE3 (/IMP) H8ESE4 (/IMP) H8ESE5 (/IMP)
(1 more)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
11 H7BRC9 (/IGI) H7BRM4 (/IGI) H7BRM5 (/IGI) H7BRM7 (/IGI) H8ESD6 (/IGI) H8ESD8 (/IGI) H8ESE2 (/IGI) H8ESE3 (/IGI) H8ESE4 (/IGI) H8ESE5 (/IGI)
(1 more)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
11 H7BRC9 (/IMP) H7BRM4 (/IMP) H7BRM5 (/IMP) H7BRM7 (/IMP) H8ESD6 (/IMP) H8ESD8 (/IMP) H8ESE2 (/IMP) H8ESE3 (/IMP) H8ESE4 (/IMP) H8ESE5 (/IMP)
(1 more)
Behavioral response to ethanol GO:0048149
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
11 H7BRC9 (/IMP) H7BRM4 (/IMP) H7BRM5 (/IMP) H7BRM7 (/IMP) H8ESD6 (/IMP) H8ESD8 (/IMP) H8ESE2 (/IMP) H8ESE3 (/IMP) H8ESE4 (/IMP) H8ESE5 (/IMP)
(1 more)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
11 H7BRC9 (/IGI) H7BRM4 (/IGI) H7BRM5 (/IGI) H7BRM7 (/IGI) H8ESD6 (/IGI) H8ESD8 (/IGI) H8ESE2 (/IGI) H8ESE3 (/IGI) H8ESE4 (/IGI) H8ESE5 (/IGI)
(1 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 Q28204 (/ISA) Q28265 (/ISA)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q28204 (/ISA) Q28265 (/ISA)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
2 Q28204 (/ISA) Q28265 (/ISA)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 Q28204 (/ISA) Q28265 (/ISA)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
2 Q28204 (/ISA) Q28265 (/ISA)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
2 Q28204 (/ISA) Q28265 (/ISA)
Adult walking behavior GO:0007628
The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
2 Q28204 (/ISA) Q28265 (/ISA)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
2 B7ZC96 (/IMP) F1QYL4 (/IMP)
Neuronal action potential GO:0019228
An action potential that occurs in a neuron.
2 Q28204 (/ISA) Q28265 (/ISA)
Cellular potassium ion homeostasis GO:0030007
Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.
2 Q28204 (/ISA) Q28265 (/ISA)
Regulation of aldosterone metabolic process GO:0032344
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
2 Q28204 (/ISA) Q28265 (/ISA)
Response to carbon monoxide GO:0034465
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
2 Q28204 (/ISA) Q28265 (/ISA)
Vasodilation GO:0042311
An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
2 Q28204 (/ISA) Q28265 (/ISA)
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 Q28204 (/ISA) Q28265 (/ISA)
Inner ear auditory receptor cell differentiation GO:0042491
The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.
2 Q28204 (/ISA) Q28265 (/ISA)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 Q28204 (/ISA) Q28265 (/ISA)
Locomotor rhythm GO:0045475
The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
2 Q28204 (/ISA) Q28265 (/ISA)
Negative regulation of cell volume GO:0045794
Any process that decreases cell volume.
2 Q28204 (/ISA) Q28265 (/ISA)
Saliva secretion GO:0046541
The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.
2 Q28204 (/ISA) Q28265 (/ISA)
Cell maturation GO:0048469
A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
2 Q28204 (/ISA) Q28265 (/ISA)
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
2 Q28204 (/ISA) Q28265 (/ISA)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
2 Q28204 (/ISA) Q28265 (/ISA)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
2 Q28204 (/ISA) Q28265 (/ISA)
Micturition GO:0060073
The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
2 Q28204 (/ISA) Q28265 (/ISA)
Eye blink reflex GO:0060082
The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.
2 Q28204 (/ISA) Q28265 (/ISA)
Smooth muscle contraction involved in micturition GO:0060083
The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.
2 Q28204 (/ISA) Q28265 (/ISA)
Relaxation of vascular smooth muscle GO:0060087
A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
2 Q28204 (/ISA) Q28265 (/ISA)
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
2 Q28204 (/ISA) Q28265 (/ISA)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 Q12791 (/IDA)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q03720 (/NAS)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q12791 (/IDA)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
1 Q03720 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
1 Q03720 (/IMP)
Cellular potassium ion homeostasis GO:0030007
Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.
1 Q12791 (/IDA)
Response to carbon monoxide GO:0034465
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
1 Q12791 (/IDA)
Response to carbon monoxide GO:0034465
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
1 Q12791 (/IMP)
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 Q12791 (/IDA)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 Q12791 (/IMP)
Male courtship behavior, veined wing generated song production GO:0045433
The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.
1 Q03720 (/IMP)
Male courtship behavior, veined wing generated song production GO:0045433
The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.
1 Q03720 (/NAS)
Negative regulation of cell volume GO:0045794
Any process that decreases cell volume.
1 Q12791 (/IDA)
Circadian behavior GO:0048512
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
1 Q03720 (/IMP)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q12791 (/IDA)
Micturition GO:0060073
The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
1 Q12791 (/IDA)
Smooth muscle contraction involved in micturition GO:0060083
The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.
1 Q12791 (/IDA)
Relaxation of vascular smooth muscle GO:0060087
A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
1 O18866 (/IMP)
Negative regulation of neuromuscular synaptic transmission GO:1900074
Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.
1 Q03720 (/IMP)
Positive regulation of membrane hyperpolarization GO:1902632
Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization.
1 O18866 (/IMP)

There are 23 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
M band GO:0031430
The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.
11 H7BRC9 (/IDA) H7BRM4 (/IDA) H7BRM5 (/IDA) H7BRM7 (/IDA) H8ESD6 (/IDA) H8ESD8 (/IDA) H8ESE2 (/IDA) H8ESE3 (/IDA) H8ESE4 (/IDA) H8ESE5 (/IDA)
(1 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
11 H7BRC9 (/IDA) H7BRM4 (/IDA) H7BRM5 (/IDA) H7BRM7 (/IDA) H8ESD6 (/IDA) H8ESD8 (/IDA) H8ESE2 (/IDA) H8ESE3 (/IDA) H8ESE4 (/IDA) H8ESE5 (/IDA)
(1 more)
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
11 H7BRC9 (/IDA) H7BRM4 (/IDA) H7BRM5 (/IDA) H7BRM7 (/IDA) H8ESD6 (/IDA) H8ESD8 (/IDA) H8ESE2 (/IDA) H8ESE3 (/IDA) H8ESE4 (/IDA) H8ESE5 (/IDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q28204 (/ISA) Q28265 (/ISA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 Q28204 (/ISA) Q28265 (/ISA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q28204 (/ISA) Q28265 (/ISA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q12791 (/TAS) Q28265 (/TAS)
Caveola GO:0005901
A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.
2 Q28204 (/ISA) Q28265 (/ISA)
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
2 Q28204 (/ISA) Q28265 (/ISA)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
2 Q28204 (/ISA) Q28265 (/ISA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q28204 (/ISA) Q28265 (/ISA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 Q28204 (/ISA) Q28265 (/ISA)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
2 Q28204 (/ISA) Q28265 (/ISA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
2 Q28204 (/ISA) Q28265 (/ISA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 Q28204 (/ISA) Q28265 (/ISA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q03720 (/NAS)
Caveola GO:0005901
A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.
1 Q12791 (/IDA)
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
1 Q12791 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q03720 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q12791 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
1 Q12791 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q03720 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q03720 (/IDA)