The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 738: Galactose/lactose metabolism regulatory protein GA...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
|
7 | P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) |
|
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
|
7 | P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) |
|
Kinase inhibitor activity GO:0019210
Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
7 | P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
7 | P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
7 | P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) |
|
Galactose metabolic process GO:0006012
The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
|
7 | P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) P04387 (/IMP) |
|
Negative regulation of kinase activity GO:0033673
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
7 | P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) |
|
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
7 | P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) |
|
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
7 | P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) P04387 (/IPI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
7 | P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) P04387 (/IDA) |