The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 600: 17-beta-hydroxysteroid dehydrogenase 14
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Estradiol 17-beta-dehydrogenase activity GO:0004303
Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+.
|
2 | Q9BPX1 (/IDA) Q9BPX1 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9BPX1 (/IPI) Q9BPX1 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | Q9BPX1 (/IPI) Q9BPX1 (/IPI) |
|
Testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045
Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
|
2 | Q9BPX1 (/IDA) Q9BPX1 (/IDA) |
|
Estradiol 17-beta-dehydrogenase activity GO:0004303
Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+.
|
1 | E9Q3D4 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | E9Q3D4 (/ISO) |
|
Testosterone 17-beta-dehydrogenase (NADP+) activity GO:0047045
Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
|
1 | E9Q3D4 (/ISO) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Estrogen biosynthetic process GO:0006703
The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
|
2 | Q9BPX1 (/TAS) Q9BPX1 (/TAS) |
|
Steroid catabolic process GO:0006706
The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
|
2 | Q9BPX1 (/IDA) Q9BPX1 (/IDA) |
|
Steroid catabolic process GO:0006706
The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
|
1 | E9Q3D4 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9BPX1 (/IDA) Q9BPX1 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q9BPX1 (/TAS) Q9BPX1 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | E9Q3D4 (/ISO) |
