The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 509: Short chain dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
4 Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA)
Glycerol dehydrogenase [NAD+] activity GO:0008888
Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH.
4 Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
4 Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
3 A0QYC2 (/IDA) A0QYC2 (/IDA) A0QYC2 (/IDA)
Erythrulose reductase activity GO:0047880
Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH.
3 A0QYC2 (/IDA) A0QYC2 (/IDA) A0QYC2 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycerol catabolic process GO:0019563
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
4 Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA) Q92EU6 (/IDA)
Carbohydrate utilization GO:0009758
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.
3 A0QYC2 (/IMP) A0QYC2 (/IMP) A0QYC2 (/IMP)
Carbohydrate catabolic process GO:0016052
The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
3 A0QYC2 (/IMP) A0QYC2 (/IMP) A0QYC2 (/IMP)
Cellular response to carbohydrate stimulus GO:0071322
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
3 A0QYC2 (/IDA) A0QYC2 (/IDA) A0QYC2 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.