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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 48: 4-hydroxy-tetrahydrodipicolinate reductase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
4-hydroxy-tetrahydrodipicolinate reductase GO:0008839
Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.
 22 P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA)
(12 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 22 P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA)
(12 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 11 P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI) P63895 (/IPI)
(1 more)
4-hydroxy-tetrahydrodipicolinate reductase GO:0008839
Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.
 3 Q9KPH7 (/ISS) Q9KPH7 (/ISS) Q9KPH7 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
 22 P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA)
(12 more)
Diaminopimelate biosynthetic process GO:0019877
The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
 22 P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA)
(12 more)
Diaminopimelate biosynthetic process GO:0019877
The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
 22 P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP) P04036 (/IMP)
(12 more)
Lysine biosynthetic process via diaminopimelate GO:0009089
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
 3 Q9KPH7 (/ISS) Q9KPH7 (/ISS) Q9KPH7 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 22 P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA) P04036 (/HDA)
(12 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 22 P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA) P04036 (/IDA)
(12 more)