The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 369: flavin reductase (NADPH)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Biliverdin reductase activity GO:0004074
Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
3 P52556 (/ISS) Q923D2 (/ISS) Q923D2 (/ISS)
Riboflavin reductase (NADPH) activity GO:0042602
Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
3 P52556 (/ISS) Q923D2 (/ISS) Q923D2 (/ISS)
Biliverdin reductase activity GO:0004074
Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
2 P30043 (/IDA) P30043 (/IDA)
Biliverdin reductase activity GO:0004074
Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
2 Q923D2 (/ISO) Q923D2 (/ISO)
Biliverdin reductase activity GO:0004074
Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
2 P30043 (/TAS) P30043 (/TAS)
Riboflavin reductase (NADPH) activity GO:0042602
Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
2 P30043 (/IDA) P30043 (/IDA)
Riboflavin reductase (NADPH) activity GO:0042602
Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
2 Q923D2 (/ISO) Q923D2 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heme catabolic process GO:0042167
The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
3 P52556 (/ISS) Q923D2 (/ISS) Q923D2 (/ISS)
Heme catabolic process GO:0042167
The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
2 P30043 (/IDA) P30043 (/IDA)
Heme catabolic process GO:0042167
The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
2 Q923D2 (/ISO) Q923D2 (/ISO)
Heme catabolic process GO:0042167
The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
2 P30043 (/TAS) P30043 (/TAS)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 P30043 (/IDA) P30043 (/IDA) V9HWI1 (/IDA) V9HWI1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P30043 (/IDA) P30043 (/IDA) V9HWI1 (/IDA) V9HWI1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P30043 (/IDA) P30043 (/IDA) V9HWI1 (/IDA) V9HWI1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P52556 (/ISS) Q923D2 (/ISS) Q923D2 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q923D2 (/ISO) Q923D2 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q923D2 (/ISO) Q923D2 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P30043 (/TAS) P30043 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q923D2 (/ISO) Q923D2 (/ISO)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
2 Q923D2 (/ISO) Q923D2 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P30043 (/HDA) P30043 (/HDA)
Terminal bouton GO:0043195
Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
1 B5DF65 (/IDA)