The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 329: Corticosteroid 11-beta-dehydrogenase isozyme 1

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
11-beta-hydroxysteroid dehydrogenase. [EC: 1.1.1.146]
An 11-beta-hydroxysteroid + NADP(+) = an 11-oxosteroid + NADPH.
    12 P16232 P28845 P28845 P50172 P50172 P51975 Q29608 Q4JHD9 Q4JHD9 Q7M3I4
    (2 more...)
    CATH-Gene3D is a Global Biodata Core Resource Learn more...