The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 294: Glycerol-3-phosphate dehydrogenase [NAD(+)]

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367
Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
14 C8VTT9 (/IMP) P41911 (/IMP) P41911 (/IMP) P41911 (/IMP) P41911 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP)
(4 more)
Glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367
Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
3 C8VTT9 (/RCA) Q5AY38 (/RCA) Q5AY38 (/RCA)
Glycerol-3-phosphate dehydrogenase [NAD+] activity GO:0004367
Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
1 C8VTT9 (/IGI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADH oxidation GO:0006116
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
13 P41911 (/IMP) P41911 (/IMP) P41911 (/IMP) P41911 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP)
(3 more)
Intracellular accumulation of glycerol GO:0006973
The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.
9 Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP)
Protein import into peroxisome matrix GO:0016558
The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.
9 Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP) Q00055 (/IMP)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
4 P41911 (/IMP) P41911 (/IMP) P41911 (/IMP) P41911 (/IMP)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
3 C8VTT9 (/RCA) Q5AY38 (/RCA) Q5AY38 (/RCA)
Cell-abiotic substrate adhesion GO:0036164
The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.
2 Q59XU9 (/IMP) Q59XU9 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
13 P41911 (/HDA) P41911 (/HDA) P41911 (/HDA) P41911 (/HDA) Q00055 (/HDA) Q00055 (/HDA) Q00055 (/HDA) Q00055 (/HDA) Q00055 (/HDA) Q00055 (/HDA)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q6FWJ7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
9 Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA) Q00055 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 P41911 (/IDA) P41911 (/IDA) P41911 (/IDA) P41911 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P41911 (/TAS) P41911 (/TAS) P41911 (/TAS) P41911 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 Q59W33 (/IDA) Q59W33 (/IDA)