The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 222: Glucose-6-phosphate 1-dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose-6-phosphate dehydrogenase activity GO:0004345
Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
11 O00091 (/IDA) Q43727 (/IDA) Q8L743 (/IDA) Q8L743 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FY99 (/IDA) Q9FY99 (/IDA) Q9LK23 (/IDA)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q43727 (/IPI) Q8L743 (/IPI) Q8L743 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
10 Q43727 (/IDA) Q8L743 (/IDA) Q8L743 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FY99 (/IDA) Q9FY99 (/IDA) Q9LK23 (/IDA) Q9LK23 (/IDA)
Pentose-phosphate shunt, oxidative branch GO:0009051
The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).
10 Q43727 (/IDA) Q8L743 (/IDA) Q8L743 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FY99 (/IDA) Q9FY99 (/IDA) Q9LK23 (/IDA) Q9LK23 (/IDA)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9LK23 (/IEP) Q9LK23 (/IEP)
Pentose-phosphate shunt, oxidative branch GO:0009051
The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).
1 O00091 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
6 F4I0Y8 (/ISS) Q43727 (/ISS) Q8L743 (/ISS) Q8L743 (/ISS) Q9FY99 (/ISS) Q9FY99 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9FJI5 (/IDA) Q9LK23 (/IDA) Q9LK23 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 Q9FJI5 (/ISS) Q9FJI5 (/ISS) Q9FJI5 (/ISS) Q9LK23 (/ISS) Q9LK23 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
3 Q43727 (/IDA) Q9LK23 (/IDA) Q9LK23 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
3 Q43727 (/IDA) Q9FY99 (/IDA) Q9FY99 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O00091 (/HDA)