The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 212: Glutamate dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamate dehydrogenase (NAD+) activity GO:0004352
Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.
11 P39633 (/IDA) P39633 (/IDA) P39633 (/IDA) P39633 (/IDA) P39633 (/IDA) P39633 (/IDA) P39633 (/IDA) P39633 (/IDA) Q38946 (/IDA) Q38946 (/IDA)
(1 more)
Glutamate dehydrogenase (NAD+) activity GO:0004352
Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.
8 P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P39633 (/IPI) P39633 (/IPI) P39633 (/IPI) P39633 (/IPI) P39633 (/IPI) P39633 (/IPI) P39633 (/IPI) P39633 (/IPI)
Glutamate dehydrogenase [NAD(P)+] activity GO:0004353
Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.
6 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q43314 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
6 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q43314 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
6 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q43314 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
6 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q43314 (/IDA)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
6 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q43314 (/IDA)
Glutamate dehydrogenase (NAD+) activity GO:0004352
Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.
5 P28997 (/IMP) P28997 (/IMP) P50735 (/IMP) P50735 (/IMP) P50735 (/IMP)
Glutamate dehydrogenase [NAD(P)+] activity GO:0004353
Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.
3 Q43314 (/IMP) Q43314 (/IMP) Q43314 (/IMP)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
17 Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q38946 (/IEP) Q38946 (/IEP) Q38946 (/IEP)
(7 more)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
13 P28997 (/IMP) P28997 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP)
(3 more)
Cellular response to nitrogen starvation GO:0006995
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
13 Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q6H3Y7 (/IEP) Q6H3Y7 (/IEP) Q6H3Y7 (/IEP)
(3 more)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
13 P28997 (/IMP) P28997 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP) P39633 (/IMP)
(3 more)
Response to alkaline pH GO:0010446
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
11 Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q6H3Y7 (/IEP) Q6H3Y7 (/IEP) Q6H3Y7 (/IEP)
(1 more)
Response to nitrogen compound GO:1901698
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
9 Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q852M0 (/IEP) Q852M0 (/IEP)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
8 P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
8 P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS) P27346 (/ISS)
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
7 Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP) Q33E23 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
6 Q38946 (/IEP) Q38946 (/IEP) Q38946 (/IEP) Q43314 (/IEP) Q43314 (/IEP) Q43314 (/IEP)
Nitrogen compound metabolic process GO:0006807
The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
3 Q43314 (/IMP) Q43314 (/IMP) Q43314 (/IMP)
Response to absence of light GO:0009646
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
3 Q43314 (/IEP) Q43314 (/IEP) Q43314 (/IEP)
Regulation of nitrogen compound metabolic process GO:0051171
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
2 Q9S7A0 (/IEP) Q9S7A0 (/IEP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
8 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q43314 (/IDA) Q9S7A0 (/IDA) Q9S7A0 (/IDA)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
3 Q38946 (/IDA) Q38946 (/IDA) Q38946 (/IDA)