The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 158: Zinc-binding alcohol dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alcohol dehydrogenase (NADP+) activity GO:0008106
Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
13 P25377 (/IDA) P25377 (/IDA) P25377 (/IDA) P25377 (/IDA) P25377 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA)
(3 more)
Hydroxymethylfurfural reductase (NADH) activity GO:0033833
Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.
8 Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP)
Hydroxymethylfurfural reductase (NADPH) activity GO:0033845
Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.
8 Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P25377 (/IPI) P25377 (/IPI) P25377 (/IPI) P25377 (/IPI) P25377 (/IPI)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
13 P25377 (/IDA) P25377 (/IDA) P25377 (/IDA) P25377 (/IDA) P25377 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA)
(3 more)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
8 Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA) Q04894 (/IDA)
Furaldehyde metabolic process GO:0033859
The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.
8 Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP) Q04894 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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