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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1318: Long-chain acyl-[acyl-carrier-protein] reductase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Long-chain acyl-[acyl-carrier-protein] reductase. [EC: 1.2.1.80]
A long-chain aldehyde + an [acyl-carrier protein] + NAD(P)(+) = a long- chain acyl-[acyl-carrier protein] + NAD(P)H.
  • Catalyzes the reaction in the opposite direction.
  • This enzyme, purified from the cyanobacterium Synechococcus elongatus PCC 7942, catalyzes the NAD(P)H-dependent reduction of an activated fatty acid (acyl-[acp]) to the corresponding aldehyde.
  • Together with EC 4.1.99.5, it is involved in alkane biosynthesis.
  • The natural substrates of the enzyme are C16 to C18 activated fatty acids.
 4 L8ARA2 L8ARA2 Q55687 Q55687