The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 119: 3-hydroxyisobutyrate dehydrogenase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
3-hydroxyisobutyrate dehydrogenase activity GO:0008442
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
|
7 | P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) Q9SUC0 (/IDA) |
|
3-hydroxyisobutyrate dehydrogenase activity GO:0008442
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
|
7 | P29266 (/ISS) Q2HJD7 (/ISS) Q5R5E7 (/ISS) Q5R5E7 (/ISS) Q99L13 (/ISS) Q9V8M5 (/ISS) Q9V8M5 (/ISS) |
|
3-hydroxyisobutyrate dehydrogenase activity GO:0008442
Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
|
1 | Q99L13 (/ISO) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q9SUC0 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Valine catabolic process GO:0006574
The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
|
6 | P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) P31937 (/IDA) |
|
Branched-chain amino acid catabolic process GO:0009083
The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
|
6 | P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) |
|
Valine catabolic process GO:0006574
The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
|
5 | P29266 (/ISS) Q2HJD7 (/ISS) Q5R5E7 (/ISS) Q5R5E7 (/ISS) Q99L13 (/ISS) |
|
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
|
2 | Q9V8M5 (/ISS) Q9V8M5 (/ISS) |
|
Leucine metabolic process GO:0006551
The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
|
1 | Q9SUC0 (/IMP) |
|
Valine metabolic process GO:0006573
The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.
|
1 | Q9SUC0 (/IMP) |
|
Valine catabolic process GO:0006574
The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
|
1 | Q99L13 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
6 | P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) P31937 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | Q99L13 (/HDA) Q9V8M5 (/HDA) Q9V8M5 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q9V8M5 (/ISS) Q9V8M5 (/ISS) |
