The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 115: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
|
14 |
Q881X4 (/ISS)
Q881X4 (/ISS)
Q881X4 (/ISS)
Q881X4 (/ISS)
Q881X4 (/ISS)
Q881X4 (/ISS)
Q881X4 (/ISS)
Q881X4 (/ISS)
Q9KMN0 (/ISS)
Q9KMN0 (/ISS)
(4 more) |
|
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
|
7 | A0A0F7RAQ0 (/ISS) A0A0F7RAQ0 (/ISS) O67610 (/ISS) P38004 (/ISS) P38004 (/ISS) Q9X248 (/ISS) Q9X248 (/ISS) |
|
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
|
5 | O67610 (/ISS) P38004 (/ISS) P38004 (/ISS) Q9X248 (/ISS) Q9X248 (/ISS) |
|
Acetoacetyl-CoA reductase activity GO:0018454
Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
|
4 | Q8I2S7 (/IDA) Q8I2S7 (/IDA) Q8I2S7 (/IDA) Q8I2S7 (/IDA) |
|
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
|
4 | Q8I2S7 (/IDA) Q8I2S7 (/IDA) Q8I2S7 (/IDA) Q8I2S7 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9L9F8 (/IPI) |
|
Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
|
1 | Q9L9F8 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
|
5 | O67610 (/ISS) P38004 (/ISS) P38004 (/ISS) Q9X248 (/ISS) Q9X248 (/ISS) |
|
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
2 | A0A0F7RAQ0 (/ISS) A0A0F7RAQ0 (/ISS) |
|
Novobiocin biosynthetic process GO:0043642
The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.
|
1 | Q9L9F8 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.