The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"NAD(P)-binding Rossmann-like Domain
".
FunFam 102: GDP-mannose 4,6-dehydratase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
GDP-mannose 4,6-dehydratase activity GO:0008446
Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.
|
17 |
P93031 (/IDA)
P93031 (/IDA)
Q387W4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
(7 more) |
|
GDP-mannose 4,6-dehydratase activity GO:0008446
Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.
|
12 |
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
(2 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P72586 (/IPI) P72586 (/IPI) Q9SNY3 (/IPI) Q9SNY3 (/IPI) |
|
GDP-mannose 4,6-dehydratase activity GO:0008446
Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.
|
2 | P93031 (/ISS) P93031 (/ISS) |
|
GDP-mannose 4,6-dehydratase activity GO:0008446
Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.
|
1 | Q387W4 (/ISM) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fucose metabolic process GO:0006004
The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose.
|
14 |
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
(4 more) |
|
GDP-mannose metabolic process GO:0019673
The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
|
14 |
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
(4 more) |
|
Lipopolysaccharide biosynthetic process GO:0009103
The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
|
12 |
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
Q51366 (/IMP)
(2 more) |
|
O antigen biosynthetic process GO:0009243
The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.
|
12 |
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
Q51366 (/IDA)
(2 more) |
|
GDP-D-rhamnose biosynthetic process GO:0019306
The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.
|
12 |
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
Q51366 (/EXP)
(2 more) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
6 | P71790 (/IEP) P71790 (/IEP) P71790 (/IEP) P71790 (/IEP) P71790 (/IEP) P71790 (/IEP) |
|
Unidimensional cell growth GO:0009826
The process in which a cell irreversibly increases in size in one
|
2 | P93031 (/IMP) P93031 (/IMP) |
|
'de novo' GDP-L-fucose biosynthetic process GO:0042351
The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
|
2 | P93031 (/IMP) P93031 (/IMP) |
|
Polysaccharide biosynthetic process GO:0000271
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
|
1 | Q387W4 (/ISM) |
|
'de novo' GDP-L-fucose biosynthetic process GO:0042351
The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
|
1 | Q387W4 (/IDA) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
15 |
Q387W4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
Q8IAX4 (/IDA)
(5 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | P71790 (/HDA) P71790 (/HDA) P71790 (/HDA) P71790 (/HDA) P71790 (/HDA) P71790 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P93031 (/IDA) P93031 (/IDA) |
|
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
|
1 | Q387W4 (/IDA) |
