The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: tRNA-specific 2-thiouridylase MnmA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
67 P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA)
(57 more)
TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity GO:0004808
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.
4 Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA wobble position uridine thiolation GO:0002143
The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
67 P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA)
(57 more)
TRNA wobble position uridine thiolation GO:0002143
The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
67 P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP)
(57 more)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
4 Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
67 P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA)
(57 more)
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