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CATH Superfamily 3.40.50.620

HUPs

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: NH(3)-dependent NAD(+) synthetase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NAD+ synthase (glutamine-hydrolyzing) activity GO:0003952
Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
 28 Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS)
(18 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 28 P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI) P18843 (/IPI)
(18 more)
NAD+ synthase activity GO:0008795
Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.
 28 P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA)
(18 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADH metabolic process GO:0006734
The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
 28 Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS)
(18 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
 28 P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP) P18843 (/IEP)
(18 more)
NAD salvage GO:0034355
Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).
 28 P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA)
(18 more)
'de novo' NAD biosynthetic process from aspartate GO:0034628
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
 28 P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA)
(18 more)
Asexual sporulation GO:0030436
The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.
 21 Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS) Q81RP3 (/ISS)
(11 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 28 P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA) P18843 (/IDA)
(18 more)