The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 106: Glutamine-dependent NAD(+) synthetase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
NAD(+) synthase. [EC: 6.3.1.5]
ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
  • L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).
42 A0A0X3Y223 A0A0X3Y223 A0A0X3Y223 A0A1W0VPS0 A0A1W0VPS0 A0A1Y3E480 A0A1Y3E480 A0A1Y3E480 A0A2J9KK38 A0A2J9KK38
(32 more...)
NAD(+) synthase (glutamine-hydrolyzing). [EC: 6.3.5.1]
ATP + deamido-NAD(+) + L-glutamine + H(2)O = AMP + diphosphate + NAD(+) + L-glutamate.
  • NH(3) can act instead of glutamine (cf. EC 6.3.1.5).
9 G4FE95 G4FE95 L8ATT8 L8ATT8 O67091 P74292 P74292 Q9X0Y0 Q9X0Y0