The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphotransferase system, mannose-type IIA component
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: PTS system mannose-specific transporter subunit II...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
116 P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI) P69797 (/IPI)
(106 more)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)
Protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity GO:0022870
Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)
Mannose transmembrane transport GO:0015761
The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)
Glucose import across plasma membrane GO:0098708
The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
116 P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA)
(106 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
116 P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA) P69797 (/IDA)
(106 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
116 P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA) P69797 (/HDA)
(106 more)