The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
von Willebrand factor, type A domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Protein transport protein SEC23Protein transport protein SEC23SEC24 homolog B, COPII coat complex componentprotein transport protein Sec24D isoform X1Complement factor Bvon Willebrand factorVesicle coat componentTranscription factor TFIIH subunit Tfb4, putativeSC:2Integrin betaIntegrin, alpha 10General transcription factor IIH subunit 2Anthrax toxin receptor 1Collagen type VI alpha 3 chainAnthrax toxin receptorX-ray repair cross-complementing protein 6 isoform X160 kDa SS-A/Ro ribonucleoproteinvon Willebrand factorX-ray repair cross-complementing protein 5von Willebrand factorSporozoite surface protein 2Collagen, type XII, alpha 1Collagen type VI alpha 3 chaincollagen alpha-6(VI) chain26S proteasome non-ATPase regulatory subunit 4voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1Calcium voltage-gated channel auxiliary subunit alpha2delta 3Putative vitrinIntegrator complex subunit 6 likeinter-alpha-trypsin inhibitor heavy chain H2von Willebrand and RING finger domain proteinCollagen type VI alpha 3 chainMatrilin 1Collagen, type VI, alpha 3Collagen type VI alpha 3 chainVitrinCollagen, type VI, alpha 1collagen alpha-2(VI) chain isoform X1MidasinCochlinProtein ViaAHemicentin 1calcium-activated chloride channel regulator 1collagen alpha-3(VI) chain isoform X3Integrin betaCollagen type VI alpha 3 chainintegrator complex subunit 14 isoform X1VWFA and cache domain-containing protein 160 kDa SS-A/Ro ribonucleoprotein isoform X1Collagen alpha-1(XXI) chain isoform X1Copine 4Protein transport protein SEC23Collagen type VI alpha 6 chaingeneral transcription factor IIH subunit 3 isoform X1von Willebrand factor A domain-containing protein 1von Willebrand factor A domain containing 2von Willebrand factor A domain-related proteinvon Willebrand factor A domain containing 8Collagen, type VI, alpha 1Collagen type XXVIII alpha 1 chaincollagen alpha-2(VI) chain isoform X1von Willebrand factor A domain containing 2Protein transport protein SEC23von Willebrand factor A domain containing 2Calcium-activated chloride channel regulator 2Collagen, type VI, alpha 1Uncharacterized protein, isoform CRNA polymerase II transcription factor B subunit 4Complement C2von Willebrand factor, type AIntegrin alpha MATP-dependent DNA helicase 2 subunit KU70von Willebrand factor A domain containing 5Asushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1ATP-dependent DNA helicase II subunit 1collagen alpha-1(VII) chainATP-dependent DNA helicase II subunit 2Mediator complex subunit 25general transcription factor IIH subunit 3Uncharacterized protein, isoform BUPF0353 protein RN09_1826Mg-protoporphyrin IX chelataseX-ray repair-complementing defective repair in Chinese hamster cells 6Collagen type VI alpha 5 chainPoly [ADP-ribose] polymeraseCircumsporozoite-and TRAP-related proteinCircumsporozoite-and TRAP-related proteinTRAP-like proteinRNA polymerase II transcription factor B subunit 4Protein transport protein Sec24ASecretory 24AB, isoform AGeneral transcription factor IIH subunitMidasinTranscription initiation factor TFIIH subunitVoltage-dependent calcium channel subunit alpha-2/delta-3Dihydropyridine-sensitive l-type calcium channelIntegrin betaProtein transport protein Sec24-like CEFCopine-5Yku70pInter alpha-trypsin inhibitor, heavy chain-like proteinGeneral transcription factor IIH subunit, putativeATP-dependent DNA helicase 2 subunit KU80Sec23/sec24 transport family proteinUnplaced genomic scaffold supercont1.1, whole genome shotgun sequenceMesocentinNitric oxide reductase D proteinPutative ribonucleoprotein related-proteinSfb3pProtein transport protein SEC23Protein CBR-DIG-1Uncharacterized proteinTFIIH basal transcription factor subunitProtein CBR-CUT-6MidasinRetroelement pol polyprotein-likeVoltage-dependent calcium channel unc-36Protein CBR-TAG-180Collagen type VI alpha 6 chainMidasinComplement factor BMidasin, putativeMesocentinProtein transport protein SEC23ATP-dependent DNA helicase II subunit 2von Willebrand factor, type AVoltage-dependent calcium channel subunit alpha-2/delta-160 kDa SS-A/Ro ribonucleoprotein homolog26S proteasome regulatory subunit S5A (AFU_orthologue AFUA_2G15070)Probable E3 ubiquitin-protein ligase EDA40Inverted repeat-binding proteinUncharacterized protein60 kDa SS-A/Ro ribonucleoprotein homologProtein transport protein Sec24C, putativeEfk-1Alpha-protein kinase vwkAC-type LECtinIntegrator complex subunit 14general transcription factor IIH subunit 3 isoform X2Predicted proteinUncharacterized protein (Fragment)Matrilin-4Integrator complex subunit 6ATP-dependent DNA helicase II subunit 2RNA polymerase II transcription factor B subunit, putativeTelomerase-associated protein 1ATP-dependent DNA helicase II subunit 2Copine family proteinMidasinPredicted proteinProtein BONZAI 2Uncharacterized proteinTFIIH P44RfeFUncharacterized proteinCollagen, type VI, alpha 1General Transcription Factor homologUncharacterized proteinPredicted proteinCalcium voltage-gated channel auxiliary subunit alpha2delta 2Caenorhabditis KUMesocentinPredicted proteinIntegrin betaLOC553407 proteinPredicted proteinCollagen, type VI, alpha 3Collagen, type VI, alpha 1ATP-dependent DNA helicaseCollagen type VI alpha 3 chainCollagen, type VI, alpha 1Tellurium resistance proteinUncharacterized proteinCollagen, type VI, alpha 1Matrilin 1Complement factor BCopine-7Uncharacterized proteinUncharacterized proteinvon Willebrand factor type A domain proteinEpithelial chloride channel proteinUncharacterized proteinUncharacterized protein, isoform EPredicted proteinProteasome 26S subunit, non-ATPase 4Uncharacterized proteinUncharacterized proteinATP-dependent DNA helicase II subunit 2Uncharacterized proteinATP-dependent DNA helicase 2 subunit KU80Circularly permutated Ras protein 1Protein transport protein SEC23Integrin betaUbiquitin-conjugating enzyme family proteinCollagen, type VII, alpha 1Protein transport protein SEC23Uncharacterized proteinIntegrin betaIntegrin betaProtein transport protein SEC23ATP-dependent DNA helicase II subunit 2Predicted proteinATP-dependent DNA helicase II subunit 1KU80 proteinATP-dependent DNA helicase II subunit 2Integrin betaDNA binding proteinCku-70Voltage-dependent calcium channel subunit alpha-2/delta-1Ku70-like proteinATP-dependent DNA helicase II subunit 1von Willebrand factorPutative KU70 proteinATP-dependent DNA helicaseATP-dependent DNA helicase II subunit 1Collagen, type VI, alpha 4avon Willebrand factorUncharacterized proteinUncharacterized proteinABL030Wpvon Willebrand factorCollagen, type VI, alpha 4aMidasinUncharacterized proteinIntegrin betaIntegrin betaAGAP009043-PACollagen alpha-1(XIV) chain-likeUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinPutative 60 kd ribonucleoprotein ssa/ro60 kd ribonucleoprotein ssa/roUncharacterized proteinPredicted proteinDumPY: shorter than wild-typevon Willebrand factor type A domain containing protein, putativeIntegrator complex subunit 14TROVE domain proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinintegrator complex subunit 14VWA domain containing CoxE-like proteinUncharacterized proteinUncharacterized protein60-kDa SS-A/Ro ribonucleoprotein homologGeneral transcription and DNA repair factor IIH subunit TFB4Methanol oxidation proteinUncharacterized proteinUncharacterized proteinCutl-23Cutl-23ANTXR cell adhesion molecule 1dANTXR cell adhesion molecule 1dPredicted proteinVoltage-dependent calcium channel subunit alpha-2/delta-3voltage-dependent calcium channel subunit alpha-2/delta-3-like isoform X1Voltage-dependent calcium channel subunit alpha-2/delta-4Uncharacterized proteinPredicted proteinPredicted proteinUncharacterized proteinCalcium voltage-gated channel auxiliary subunit alpha2delta 4Integrin betaPredicted proteinUncharacterized proteinCollagen, type XII, alpha 1bUncharacterized proteinUncharacterized proteinDNA binding proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinATP-dependent DNA helicase II subunit 2Protein transport protein SEC23Integrin betaUncharacterized proteinIntegrin betaUncharacterized proteinIntegrin betaUncharacterized proteinUncharacterized proteinProtein transport protein SEC23Integrin betaIntegrin betaKU70 proteinInverted repeat-binding proteinUncharacterized proteinX-ray repair cross-complementing protein 5-like ProteinUncharacterized proteinCollagen type VI alpha 3 chainPredicted proteinPredicted proteinPredicted proteinUbiquitin interaction motif family proteinPoly [ADP-ribose] polymeraseUbiquitin-conjugating enzyme family proteinSec24d proteinIntegrin betaUncharacterized proteinATP dependent DNA ligase 1Uncharacterized proteinSerine/threonine protein kinase PpkAIntegrin betaUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMesocentinUncharacterized proteinUncharacterized proteinPhospholipase A(2)Integrin betaIntegrin betaPredicted proteinUncharacterized proteinUncharacterized proteinCollagen, type XIV, alpha 1aIntegrin betaUncharacterized proteinUncharacterized proteinProtein transport protein SEC2360 kDa SS-A/Ro ribonucleoprotein-like ProteinIntegrin betaTFIIH P34Uncharacterized proteinProtein transport protein SEC23Uncharacterized proteinChloride channel accessory 3, pseudogeneUncharacterized proteinSec24-related gene family, member C (S. cerevisiae)AGAP001871-PAUncharacterized proteinUncharacterized proteinFibronectin binding proteinUncharacterized proteinPredicted proteinUncharacterized proteinAnthrax toxin receptorIntegrin beta-like protein CUncharacterized proteinUncharacterized proteinUncharacterized proteinIntegrin betaProteasome 26S subunit, non-ATPase 4Uncharacterized proteinProtein transport protein SEC23Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinVwa2 proteinUncharacterized proteinProtein transport protein SEC23TFIIH 34kDa subunitCollagen, type VI, alpha 3Bcl-2-associated transcription factor (BTF), putativeUncharacterized proteinUncharacterized proteinType IV pili system adhesin PilYGeneral transcription and DNA repair factor IIH subunit tfb4MxaL proteinUncharacterized proteinUncharacterized proteinPredicted protein60 kDa SS-A/Ro ribonucleoprotein homologUncharacterized proteinPredicted proteinUncharacterized proteinvoltage-dependent calcium channel subunit alpha-2/delta-1Voltage-dependent calcium channel subunit alpha-2/delta-4-like ProteinCalcium voltage-gated channel auxiliary subunit alpha2delta 3Uncharacterized proteinUncharacterized proteinCollagen alpha 3 chain type VI
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FunFam 37: Collagen type VI alpha 3 chain

GO Diversity

Unique GO annotations
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EC Diversity

Unique EC annotations
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Species Diversity

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Statistics

Members
CATH Domains: 0
Sequences: 131
Annotations
Unique GO: 13
Unique EC: 0
Unique Species: 39
Representative
Rep ID: P12111/1832-2031
Inherited Annotations: 0
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