The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 679: Thymidylate kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
5 P23919 (/IDA) P23919 (/IDA) P23919 (/IDA) P23919 (/IDA) P97930 (/IDA)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
4 A1ZB29 (/ISS) Q54GN2 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
4 P23919 (/TAS) P23919 (/TAS) P23919 (/TAS) P23919 (/TAS)
Uridylate kinase activity GO:0009041
Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.
4 A1ZB29 (/ISS) Q54GN2 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
1 P36590 (/IGI)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
1 P97930 (/ISO)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
1 C8V778 (/RCA)
Uridylate kinase activity GO:0009041
Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.
1 P36590 (/IGI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DUDP biosynthetic process GO:0006227
The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).
4 A1ZB29 (/ISS) Q54GN2 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
4 A1ZB29 (/ISS) Q54GN2 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
4 A1ZB29 (/ISS) Q54GN2 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
4 P23919 (/TAS) P23919 (/TAS) P23919 (/TAS) P23919 (/TAS)
Thymidine biosynthetic process GO:0046105
The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
4 P23919 (/TAS) P23919 (/TAS) P23919 (/TAS) P23919 (/TAS)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
2 D3ZUJ5 (/IDA) P97930 (/IDA)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q0WW55 (/IMP) Q0WW55 (/IMP)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
1 C8V778 (/RCA)
DUDP biosynthetic process GO:0006227
The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).
1 P36590 (/IGI)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
1 P36590 (/IGI)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
1 P97930 (/ISO)
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
1 D3ZUJ5 (/IDA)
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
1 P36590 (/IGI)
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
1 P97930 (/ISO)
Nucleotide biosynthetic process GO:0009165
The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
1 P97930 (/IDA)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 D3ZUJ5 (/IEP)
Myoblast differentiation GO:0045445
The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
1 D3ZUJ5 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 D3ZUJ5 (/IEP)
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
1 P97930 (/IDA)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 D3ZUJ5 (/IDA) F4KJ62 (/IDA) Q0WW55 (/IDA) Q0WW55 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P23919 (/TAS) P23919 (/TAS) P23919 (/TAS) P23919 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 A1ZB29 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 F4KJ62 (/IDA) Q0WW55 (/IDA) Q0WW55 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 F4KJ62 (/IDA) Q0WW55 (/IDA) Q0WW55 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 A1ZB29 (/ISS) Q7K2J3 (/ISS) Q8SZQ0 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P36590 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P97930 (/ISO)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 D3ZUJ5 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 P97930 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 D3ZUJ5 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 P97930 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P36590 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 F4KJ62 (/IDA)