The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 541: Immunity related GTPase M
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
16 |
A0A140LIF8 (/ISS)
A0A2R8RQN4 (/ISS)
A0A2R8RR87 (/ISS)
A2RV34 (/ISS)
A5WVI1 (/ISS)
A9JRC3 (/ISS)
E7F6D1 (/ISS)
F1Q673 (/ISS)
F1QXG9 (/ISS)
Q3TAN6 (/ISS)
(6 more) |
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
11 |
Q3U5T3 (/IDA)
Q62293 (/IDA)
Q62293 (/IDA)
Q62293 (/IDA)
Q811M6 (/IDA)
Q8C2M8 (/IDA)
Q8K242 (/IDA)
Q9DCE9 (/IDA)
Q9QZ85 (/IDA)
Q9QZ85 (/IDA)
(1 more) |
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
8 | A0A2R8RQN4 (/ISS) A0A2R8RR87 (/ISS) A2RV34 (/ISS) A5WVI1 (/ISS) A9JRC3 (/ISS) E7F6D1 (/ISS) F1Q673 (/ISS) F1QXG9 (/ISS) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Protein serine/threonine kinase activator activity GO:0043539
Binds to and increases the activity of a protein serine/threonine kinase.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
CARD domain binding GO:0050700
Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
BH3 domain binding GO:0051434
Interacting selectively and non-covalently with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | A1A4Y4 (/IPI) Q9QZ85 (/IPI) Q9QZ85 (/IPI) Q9QZ85 (/IPI) |
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
3 | Q9QZ85 (/IDA) Q9QZ85 (/IDA) Q9QZ85 (/IDA) |
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
|
3 | Q9QZ85 (/IDA) Q9QZ85 (/IDA) Q9QZ85 (/IDA) |
Showing 1 to 10 of 16 entries
There are 57 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
13 |
A0A140LIF8 (/IEP)
Q3TAN6 (/IEP)
Q3TNE5 (/IEP)
Q3U635 (/IEP)
Q60766 (/IEP)
Q60766 (/IEP)
Q62293 (/IEP)
Q62293 (/IEP)
Q62293 (/IEP)
Q9QZ85 (/IEP)
(3 more) |
Cellular response to interferon-beta GO:0035458
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
|
11 |
Q3U5T3 (/IDA)
Q3UED7 (/IDA)
Q62293 (/IDA)
Q62293 (/IDA)
Q62293 (/IDA)
Q811M6 (/IDA)
Q8C2M8 (/IDA)
Q9DCE9 (/IDA)
Q9QZ85 (/IDA)
Q9QZ85 (/IDA)
(1 more) |
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
6 | Q3U0K0 (/IMP) Q60766 (/IMP) Q60766 (/IMP) Q61635 (/IMP) Q61635 (/IMP) Q99M59 (/IMP) |
Autophagosome assembly GO:0000045
The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Protein destabilization GO:0031648
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Positive regulation of peptidyl-serine phosphorylation GO:0033138
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Showing 1 to 10 of 57 entries
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
6 | Q3U0K0 (/TAS) Q60766 (/TAS) Q60766 (/TAS) Q61635 (/TAS) Q61635 (/TAS) Q99M59 (/TAS) |
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A1A4Y4 (/IDA) Q3U5T3 (/IDA) Q811M6 (/IDA) Q8C2M8 (/IDA) Q9DCE9 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | A0A140LIF8 (/ISO) Q3TAN6 (/ISO) Q3TNE5 (/ISO) Q3U635 (/ISO) Q9Z1M2 (/ISO) |
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
3 | Q9QZ85 (/IDA) Q9QZ85 (/IDA) Q9QZ85 (/IDA) |
Symbiont-containing vacuole membrane GO:0020005
The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.
|
3 | Q9QZ85 (/IDA) Q9QZ85 (/IDA) Q9QZ85 (/IDA) |
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
2 | Q60766 (/IDA) Q60766 (/IDA) |
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
|
2 | Q60766 (/IDA) Q60766 (/IDA) |
Showing 1 to 10 of 17 entries