The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 538: ATPase family AAA domain-containing protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
34 F6QV99 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS) P28737 (/ISS)
(24 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
32 P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) P28737 (/IPI) Q505J9 (/IPI)
(22 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
22 Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA)
(12 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9P7J5 (/ISM)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of receptor internalization GO:0002092
Any process that activates or increases the frequency, rate or extent of receptor internalization.
24 F6QV99 (/ISS) Q505J9 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS)
(14 more)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
24 F6QV99 (/ISS) Q505J9 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS)
(14 more)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
24 F6QV99 (/ISS) Q505J9 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS)
(14 more)
Negative regulation of synaptic transmission, glutamatergic GO:0051967
Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
24 F6QV99 (/ISS) Q505J9 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS)
(14 more)
Positive regulation of receptor internalization GO:0002092
Any process that activates or increases the frequency, rate or extent of receptor internalization.
22 Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP)
(12 more)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
22 Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP)
(12 more)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
22 Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP)
(12 more)
Negative regulation of synaptic transmission, glutamatergic GO:0051967
Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
22 Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP)
(12 more)
Regulation of postsynaptic neurotransmitter receptor internalization GO:0099149
Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.
22 Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA)
(12 more)
Regulation of postsynaptic neurotransmitter receptor internalization GO:0099149
Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.
22 Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP)
(12 more)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
9 P28737 (/IMP) P28737 (/IMP) P28737 (/IMP) P28737 (/IMP) P28737 (/IMP) P28737 (/IMP) P28737 (/IMP) P28737 (/IMP) P28737 (/IMP)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
2 Q9VL02 (/TAS) X2J7P4 (/TAS)
Wing disc dorsal/ventral pattern formation GO:0048190
The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
2 Q9VL02 (/IGI) X2J7P4 (/IGI)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
1 Q9P7J5 (/ISO)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
1 Q1ZXK7 (/ISS)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
1 Q9FJC9 (/IMP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
32 P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) Q9D5T0 (/HDA)
(22 more)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
24 F6QV99 (/ISS) Q505J9 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS) Q8NBU5 (/ISS)
(14 more)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
22 Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA)
(12 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
22 Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA) Q8NBU5 (/HDA)
(12 more)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
22 Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA)
(12 more)
Postsynapse GO:0098794
The part of a synapse that is part of the post-synaptic cell.
22 Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA)
(12 more)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
22 Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA) Q9D5T0 (/IDA)
(12 more)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
22 Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP) Q9D5T0 (/IMP)
(12 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) Q9FJC9 (/IDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
9 P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA) P28737 (/HDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
9 P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
9 P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA) P28737 (/IDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
2 Q1ZXK7 (/ISS) Q9P7J5 (/ISS)
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