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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 527: Tyrosine-protein kinase etk

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
 54 P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA)
(44 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 42 P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI) P38134 (/IPI)
(32 more)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
 12 P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA)
(2 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 3 P96716 (/IPI) P96716 (/IPI) P96716 (/IPI)
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
 1 Q489D4 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptidyl-tyrosine autophosphorylation GO:0038083
The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.
 54 P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA)
(44 more)
Colanic acid biosynthetic process GO:0009242
The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.
 12 P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP) P76387 (/IMP)
(2 more)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
 12 P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA)
(2 more)
Polysaccharide biosynthetic process GO:0000271
The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
 2 Q489D4 (/ISS) Q74BQ8 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 54 P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA)
(44 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 42 P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA) P38134 (/IDA)
(32 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 12 P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA)
(2 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 12 P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA) P76387 (/IDA)
(2 more)
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