The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 461: Deoxycytidine kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Deoxycytidine kinase activity GO:0004137
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
3 P27707 (/IDA) P27707 (/IDA) P48769 (/IDA)
Deoxyguanosine kinase activity GO:0004138
Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+).
3 Q16854 (/IDA) Q16854 (/IDA) Q9QX60 (/IDA)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
3 P27707 (/IDA) P27707 (/IDA) P48769 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 P43346 (/ISO) P43346 (/ISO)
Deoxycytidine kinase activity GO:0004137
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
2 P43346 (/ISO) P43346 (/ISO)
Deoxycytidine kinase activity GO:0004137
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
2 P43346 (/ISS) P43346 (/ISS)
Deoxycytidine kinase activity GO:0004137
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
2 P27707 (/TAS) P27707 (/TAS)
Deoxyguanosine kinase activity GO:0004138
Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+).
2 Q16854 (/TAS) Q16854 (/TAS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 P43346 (/ISO) P43346 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2 P43346 (/ISO) P43346 (/ISO)
Pyrimidine deoxyribonucleoside binding GO:0032548
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
2 P43346 (/ISO) P43346 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P27707 (/IPI) P27707 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P43346 (/ISO) P43346 (/ISO)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 P48769 (/IDA)
Deoxycytidine kinase activity GO:0004137
Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
1 P48769 (/IMP)
Deoxyguanosine kinase activity GO:0004138
Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+).
1 Q9QX60 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P48769 (/IDA)
Pyrimidine deoxyribonucleoside binding GO:0032548
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
1 P48769 (/IDA)
Pyrimidine deoxyribonucleoside binding GO:0032548
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
1 P48769 (/IMP)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
4 P43346 (/ISS) P43346 (/ISS) P48769 (/ISS) Q3MHR2 (/ISS)
Purine-containing compound salvage GO:0043101
Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
4 P27707 (/TAS) P27707 (/TAS) Q16854 (/TAS) Q16854 (/TAS)
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
2 P27707 (/IDA) P27707 (/IDA)
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
2 P43346 (/ISO) P43346 (/ISO)
Pyrimidine nucleotide metabolic process GO:0006220
The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
2 P27707 (/TAS) P27707 (/TAS)
Guanosine metabolic process GO:0008617
The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.
2 Q16854 (/TAS) Q16854 (/TAS)
Negative regulation of neuron projection development GO:0010977
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
2 A0A0G2K478 (/IMP) D3ZDE4 (/IMP)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
2 P43346 (/ISO) P43346 (/ISO)
Pyrimidine nucleoside salvage GO:0043097
Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.
2 P27707 (/TAS) P27707 (/TAS)
Deoxycytidine metabolic process GO:0046092
The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
2 P43346 (/ISO) P43346 (/ISO)
Purine deoxyribonucleoside metabolic process GO:0046122
The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
2 Q16854 (/IDA) Q16854 (/IDA)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
1 Q9QX60 (/TAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q9QX60 (/IDA)
Negative regulation of neuron projection development GO:0010977
Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q9QX60 (/ISO)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
1 P48769 (/IDA)
DGTP metabolic process GO:0046070
The chemical reactions and pathways involving dGTP, guanosine triphosphate.
1 Q9QX60 (/IDA)
Deoxycytidine metabolic process GO:0046092
The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
1 P48769 (/IDA)
Deoxycytidine metabolic process GO:0046092
The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
1 P48769 (/IMP)
Purine deoxyribonucleoside metabolic process GO:0046122
The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
1 Q9QX60 (/ISO)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 D6RFG8 (/IDA) F5CTF3 (/IDA) F5CTF3 (/IDA) P27707 (/IDA) P27707 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q16854 (/HDA) Q16854 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P43346 (/ISO) P43346 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q16854 (/TAS) Q16854 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 Q16854 (/TAS) Q16854 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P48769 (/IDA) Q9QX60 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P43346 (/ISO) P43346 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P27707 (/TAS) P27707 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9QX60 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9QX60 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9QX60 (/IDA)
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