The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 397: Probable ATP-dependent RNA helicase DDX4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 M9PBB5 (/IPI) M9PBB5 (/IPI) P09052 (/IPI) P09052 (/IPI) Q4Q5P5 (/IPI) Q61496 (/IPI) Q8H136 (/IPI)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
5 Q388E8 (/IDA) Q8LA13 (/IDA) Q8LA13 (/IDA) Q9M2F9 (/IDA) Q9M2F9 (/IDA)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
3 P09052 (/IDA) P09052 (/IDA) Q8H136 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
2 M9PBB5 (/IDA) M9PBB5 (/IDA)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
2 Q54QS3 (/ISS) Q65XX1 (/ISS)
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
2 M9PBB5 (/IDA) M9PBB5 (/IDA)
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
1 Q388E8 (/ISM)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q388E8 (/ISM)
RNA-dependent ATPase activity GO:0008186
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
1 D0PV95 (/IDA)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
1 Q8H136 (/IDA)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
1 Q61496 (/IMP)
RNA strand annealing activity GO:0033592
Facilitates the base-pairing of complementary single-stranded RNA.
1 D0PV95 (/IMP)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 D0PV95 (/IMP)

There are 46 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
13 A1L1Z2 (/IMP) E7EZA2 (/IMP) F1QSP5 (/IMP) F1R6M3 (/IMP) F8W3U8 (/IMP) F8W4P0 (/IMP) O42107 (/IMP) O42378 (/IMP) Q65XX1 (/IMP) Q8QFU0 (/IMP)
(3 more)
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
10 A1L1Z2 (/IEP) E7EZA2 (/IEP) F1QSP5 (/IEP) F1R6M3 (/IEP) F8W3U8 (/IEP) F8W4P0 (/IEP) O42107 (/IEP) O42378 (/IEP) Q8QFU0 (/IEP) Q8QGG8 (/IEP)
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Regulation of meiotic cell cycle GO:0051445
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
10 A1L1Z2 (/IMP) E7EZA2 (/IMP) F1QSP5 (/IMP) F1R6M3 (/IMP) F8W3U8 (/IMP) F8W4P0 (/IMP) O42107 (/IMP) O42378 (/IMP) Q8QFU0 (/IMP) Q8QGG8 (/IMP)
PiRNA biosynthetic process GO:1990511
The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
4 M9PBB5 (/IMP) M9PBB5 (/IMP) P09052 (/IMP) P09052 (/IMP)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
3 Q9NQI0 (/IMP) Q9NQI0 (/IMP) Q9NQI0 (/IMP)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Mitotic chromosome condensation GO:0007076
The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
2 M9PBB5 (/IMP) M9PBB5 (/IMP)
Germarium-derived egg chamber formation GO:0007293
Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.
2 M9PBB5 (/IMP) M9PBB5 (/IMP)
Oocyte anterior/posterior axis specification GO:0007314
Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.
2 M9PBB5 (/NAS) M9PBB5 (/NAS)
Pole plasm assembly GO:0007315
Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.
2 M9PBB5 (/IMP) M9PBB5 (/IMP)
Pole plasm assembly GO:0007315
Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Pole plasm RNA localization GO:0007316
Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
2 M9PBB5 (/IMP) M9PBB5 (/IMP)
Intracellular mRNA localization GO:0008298
Any process in which mRNA is transported to, or maintained in, a specific location within the cell.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Oocyte karyosome formation GO:0030717
The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
2 M9PBB5 (/NAS) M9PBB5 (/NAS)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
2 D0PV95 (/IGI) Q65XX1 (/IGI)
Masculinization of hermaphroditic germ-line GO:0042006
The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.
2 D0PV95 (/IGI) Q65XX1 (/IGI)
Masculinization of hermaphroditic germ-line GO:0042006
The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.
2 D0PV95 (/IMP) Q65XX1 (/IMP)
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 M9PBB5 (/IMP) M9PBB5 (/IMP)
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Regulation of oskar mRNA translation GO:0046011
Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Positive regulation of oskar mRNA translation GO:0046012
Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.
2 M9PBB5 (/NAS) M9PBB5 (/NAS)
Dorsal appendage formation GO:0046843
Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
2 M9PBB5 (/HMP) M9PBB5 (/HMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 M9PBB5 (/HMP) M9PBB5 (/HMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Positive regulation of fertilization GO:1905516
Any process that activates or increases the frequency, rate or extent of fertilization.
2 D0PV95 (/IGI) Q65XX1 (/IGI)
Positive regulation of fertilization GO:1905516
Any process that activates or increases the frequency, rate or extent of fertilization.
2 D0PV95 (/IMP) Q65XX1 (/IMP)
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
1 Q388E8 (/ISM)
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
1 Q61496 (/IMP)
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
1 Q61496 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q64060 (/IEP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q61496 (/IMP)
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
1 Q61496 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 D0PV95 (/IMP)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
1 Q61496 (/ISO)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
1 Q61496 (/IMP)
PiRNA metabolic process GO:0034587
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
1 Q61496 (/IMP)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
1 D0PV95 (/IMP)
DNA methylation involved in gamete generation GO:0043046
The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
1 Q61496 (/IMP)
PiRNA biosynthetic process GO:1990511
The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
1 Q61496 (/IMP)

There are 34 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
19 A1L1Z2 (/IDA) D0PV95 (/IDA) E7EZA2 (/IDA) F1QSP5 (/IDA) F1R6M3 (/IDA) F8W3U8 (/IDA) F8W4P0 (/IDA) M9PBB5 (/IDA) M9PBB5 (/IDA) O42107 (/IDA)
(9 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
15 D0PV95 (/IDA) M9PBB5 (/IDA) M9PBB5 (/IDA) P09052 (/IDA) P09052 (/IDA) Q388E8 (/IDA) Q61496 (/IDA) Q65XX1 (/IDA) Q91372 (/IDA) Q91372 (/IDA)
(5 more)
Pi-body GO:0071546
A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
PiP-body GO:0071547
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
10 Q3MSQ8 (/ISS) Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS) Q91372 (/ISS) Q91372 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS) Q9NQI0 (/ISS)
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
5 B2C6E9 (/IDA) Q5W5U4 (/IDA) Q61496 (/IDA) Q64060 (/IDA) Q6GWX0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q388E8 (/IDA) Q61496 (/IDA) Q91372 (/IDA) Q91372 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q4R5S7 (/ISS) Q5W5U4 (/ISS) Q64060 (/ISS) Q6GWX0 (/ISS)
Pole plasm GO:0045495
Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.
4 M9PBB5 (/IDA) M9PBB5 (/IDA) Q91372 (/IDA) Q91372 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
4 M9PBB5 (/IDA) M9PBB5 (/IDA) Q61496 (/IDA) Q64060 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
3 Q84W89 (/IDA) Q8LA13 (/IDA) Q8LA13 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 Q91372 (/IDA) Q91372 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q8LA13 (/IDA) Q8LA13 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q4Q5P5 (/ISO) Q61496 (/ISO)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
2 Q9SQV1 (/IDA) Q9SQV1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q8LA13 (/IDA) Q8LA13 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
2 Q388E8 (/IDA) Q65XX1 (/IDA)
Cytoplasmic ribonucleoprotein granule GO:0036464
A ribonucleoprotein granule located in the cytoplasm.
2 M9PBB5 (/IDA) M9PBB5 (/IDA)
Germ cell nucleus GO:0043073
The nucleus of a germ cell, a reproductive cell in multicellular organisms.
2 P09052 (/IDA) P09052 (/IDA)
P granule GO:0043186
A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
2 M9PBB5 (/TAS) M9PBB5 (/TAS)
Spectrosome GO:0045170
A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.
2 M9PBB5 (/IDA) M9PBB5 (/IDA)
Posterior cell cortex GO:0061803
The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.
2 P09052 (/IDA) P09052 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q4Q5P5 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q84W89 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q61496 (/TAS)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 Q4Q5P5 (/ISO)
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
1 Q61496 (/ISO)
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
1 Q388E8 (/IDA)
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
1 Q4Q5P5 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q61496 (/ISO)
Pi-body GO:0071546
A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
1 Q61496 (/IDA)
PiP-body GO:0071547
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
1 Q61496 (/IDA)
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
1 Q388E8 (/IDA)
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
1 Q4Q5P5 (/ISO)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 Q61496 (/IDA)
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