The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 318: ATP-dependent RNA helicase DDX19B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
P20449 (/IPI)
P20449 (/IPI)
P20449 (/IPI)
P20449 (/IPI)
Q9NUU7 (/IPI)
Q9NUU7 (/IPI)
Q9NUU7 (/IPI)
Q9NUU7 (/IPI)
Q9UMR2 (/IPI)
Q9UMR2 (/IPI)
(2 more) |
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
6 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) Q9QY15 (/IDA) Q9QY16 (/IDA) |
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
5 | Q2TBP1 (/ISS) Q9DGP9 (/ISS) Q9DGP9 (/ISS) Q9QY16 (/ISS) Q9UHL0 (/ISS) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
4 | Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) |
Helicase activity GO:0004386
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
|
4 | Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) |
RNA-dependent ATPase activity GO:0008186
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
|
4 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
3 | Q2TBP1 (/ISS) Q9QY16 (/ISS) Q9UHL0 (/ISS) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
2 | Q9DGP9 (/ISS) Q9DGP9 (/ISS) |
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
2 | Q09747 (/ISO) Q9QY15 (/ISO) |
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
2 | Q9DGP9 (/ISS) Q9DGP9 (/ISS) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9QY16 (/IDA) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9QY15 (/ISO) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9QY15 (/IDA) |
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q9QY16 (/IDA) |
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
|
1 | Q9QY15 (/ISO) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
4 | P20449 (/IMP) P20449 (/IMP) P20449 (/IMP) P20449 (/IMP) |
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
4 | Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) |
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
|
4 | P20449 (/IGI) P20449 (/IGI) P20449 (/IGI) P20449 (/IGI) |
Translational termination GO:0006415
The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
|
4 | P20449 (/IPI) P20449 (/IPI) P20449 (/IPI) P20449 (/IPI) |
Poly(A)+ mRNA export from nucleus GO:0016973
The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
|
4 | P20449 (/IMP) P20449 (/IMP) P20449 (/IMP) P20449 (/IMP) |
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
3 | Q2TBP1 (/ISS) Q9QY16 (/ISS) Q9UHL0 (/ISS) |
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
3 | Q2TBP1 (/ISS) Q9QY16 (/ISS) Q9UHL0 (/ISS) |
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
|
3 | Q2TBP1 (/ISS) Q9QY16 (/ISS) Q9UHL0 (/ISS) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
2 | A0A0G2JUH2 (/IEP) Q68FX3 (/IEP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
2 | A0A0G2JUH2 (/IDA) Q68FX3 (/IDA) |
Cytoplasmic translational termination GO:0002184
The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
|
1 | Q09747 (/ISO) |
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
1 | Q9QY15 (/IDA) |
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
|
1 | Q09747 (/ISO) |
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
1 | Q9QY15 (/IDA) |
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
|
1 | Q9QY15 (/IDA) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q54TF8 (/IMP) |
Sorocarp development GO:0030587
The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
|
1 | Q54TF8 (/IMP) |
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q61655 (/ISO) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
8 | Q9NUU7 (/HDA) Q9NUU7 (/HDA) Q9NUU7 (/HDA) Q9NUU7 (/HDA) Q9UMR2 (/HDA) Q9UMR2 (/HDA) Q9UMR2 (/HDA) Q9UMR2 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) Q9QY15 (/IDA) Q9QY16 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) Q9QY15 (/IDA) Q9QY16 (/IDA) |
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
|
4 | Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) Q9UMR2 (/TAS) |
Polysome GO:0005844
A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
|
4 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) |
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
|
4 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) |
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
4 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) |
Nuclear pore cytoplasmic filaments GO:0044614
Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.
|
4 | P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) P20449 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | Q9UMR2 (/HDA) Q9UMR2 (/HDA) Q9UMR2 (/HDA) Q9UMR2 (/HDA) |
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
|
3 | Q2TBP1 (/ISS) Q9QY16 (/ISS) Q9UHL0 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q2TBP1 (/ISS) Q9UHL0 (/ISS) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
2 | Q8BZY3 (/ISO) Q8R3C7 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q2TBP1 (/ISS) Q9UHL0 (/ISS) |
Mitochondrial cloud GO:0032019
A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.
|
2 | Q9DGP9 (/IDA) Q9DGP9 (/IDA) |
Pole plasm GO:0045495
Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.
|
2 | Q9DGP9 (/IDA) Q9DGP9 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9QY15 (/ISO) |
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | Q09747 (/HDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9QY15 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q09747 (/HDA) |
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
|
1 | Q9QY15 (/IDA) |
Nuclear pore cytoplasmic filaments GO:0044614
Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.
|
1 | O61305 (/ISS) |