The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 303: GTP-binding protein Di-Ras2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
38 O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA)
(28 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
18 O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA)
(8 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
6 Q5PR73 (/ISO) Q5PR73 (/ISO) Q5PR73 (/ISO) Q5PR73 (/ISO) Q91Z61 (/ISO) Q91Z61 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q91Z61 (/ISO) Q91Z61 (/ISO)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 Q9VH66 (/ISS) Q9VH66 (/ISS)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
3 B8A547 (/IGI) F1QSQ6 (/IGI) Q803Y2 (/IGI)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
3 B8A547 (/IMP) F1QSQ6 (/IMP) Q803Y2 (/IMP)
Trigeminal ganglion development GO:0061551
The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.
3 B8A547 (/IGI) F1QSQ6 (/IGI) Q803Y2 (/IGI)
Trigeminal ganglion development GO:0061551
The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.
3 B8A547 (/IMP) F1QSQ6 (/IMP) Q803Y2 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
2 Q9VH66 (/ISS) Q9VH66 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
38 O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA) O95057 (/IDA)
(28 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 Q5PR73 (/ISO) Q5PR73 (/ISO) Q5PR73 (/ISO) Q5PR73 (/ISO) Q91Z61 (/ISO) Q91Z61 (/ISO)