The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 281: ADP-ribosylation factor-like protein 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
30 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS)
(20 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
30 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS)
(20 more)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
30 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS)
(20 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 O45379 (/IPI) P36405 (/IPI) P36405 (/IPI) P36405 (/IPI) P36405 (/IPI) P36405 (/IPI) Q57XJ5 (/IPI) Q57XJ5 (/IPI) Q57XJ5 (/IPI) Q57XJ5 (/IPI)
(3 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
9 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P37996 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
9 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P37996 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
5 P36405 (/TAS) P36405 (/TAS) P36405 (/TAS) P36405 (/TAS) P36405 (/TAS)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
3 Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
3 Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
3 Q9VD64 (/ISA) Q9VD64 (/ISA) Q9VD64 (/ISA)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
GDP binding GO:0019003
Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
GTPase activating protein binding GO:0032794
Interacting selectively and non-covalently with a GTPase activating protein.
3 Q9WUL7 (/IPI) Q9WUL7 (/IPI) Q9WUL7 (/IPI)

There are 29 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
33 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P37996 (/ISS) Q2TBW6 (/ISS)
(23 more)
Photoreceptor cell development GO:0042461
Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
33 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P37996 (/ISS) Q2TBW6 (/ISS)
(23 more)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
31 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS) Q52NJ4 (/ISS) Q52NJ4 (/ISS)
(21 more)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
31 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS) Q52NJ4 (/ISS) Q52NJ4 (/ISS)
(21 more)
Golgi to plasma membrane transport GO:0006893
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
29 P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P37996 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS)
(19 more)
Protein localization to ciliary membrane GO:1903441
A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
29 P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P36405 (/ISS) P37996 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q52NJ4 (/ISS)
(19 more)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
12 P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) Q1MTE5 (/IMP) Q1MTE5 (/IMP) Q1MTE5 (/IMP) Q57XJ5 (/IMP) Q57XJ5 (/IMP)
(2 more)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
5 P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP)
Post-Golgi vesicle-mediated transport GO:0006892
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
5 P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Cilium organization GO:0044782
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
5 E9ADU4 (/IMP) Q57XJ5 (/IMP) Q57XJ5 (/IMP) Q57XJ5 (/IMP) Q57XJ5 (/IMP)
Protein localization to cilium GO:0061512
A process in which a protein is transported to, or maintained in, a location within a cilium.
5 P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP) P36405 (/IMP)
Regulation of axon extension involved in axon guidance GO:0048841
Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.
4 A0A140LG87 (/IMP) Q6DI21 (/IMP) Q6PC43 (/IMP) Q6PC92 (/IMP)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
3 Q9WUL7 (/IMP) Q9WUL7 (/IMP) Q9WUL7 (/IMP)
Post-Golgi vesicle-mediated transport GO:0006892
The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Golgi to plasma membrane transport GO:0006893
The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
3 Q9WUL7 (/IMP) Q9WUL7 (/IMP) Q9WUL7 (/IMP)
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
3 Q9WUL7 (/IMP) Q9WUL7 (/IMP) Q9WUL7 (/IMP)
Small GTPase mediated signal transduction GO:0007264
Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Branch fusion, open tracheal system GO:0035147
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
3 Q9VD64 (/IMP) Q9VD64 (/IMP) Q9VD64 (/IMP)
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
3 Q9WUL7 (/IMP) Q9WUL7 (/IMP) Q9WUL7 (/IMP)
Photoreceptor cell development GO:0042461
Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
3 Q9WUL7 (/IMP) Q9WUL7 (/IMP) Q9WUL7 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
3 Q9VD64 (/ISM) Q9VD64 (/ISM) Q9VD64 (/ISM)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Protein localization to cilium GO:0061512
A process in which a protein is transported to, or maintained in, a location within a cilium.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Protein localization to ciliary membrane GO:1903441
A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
3 Q9WUL7 (/IMP) Q9WUL7 (/IMP) Q9WUL7 (/IMP)
Regulation of axon extension involved in axon guidance GO:0048841
Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.
2 A0A140LG87 (/IGI) Q6PC43 (/IGI)
Optomotor response GO:0071632
Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.
2 A0A140LG87 (/IMP) Q6PC43 (/IMP)

There are 32 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
34 B5FYQ0 (/ISS) B5FYQ0 (/ISS) B5FYQ0 (/ISS) P37996 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q1MTE5 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS) Q2TBW6 (/ISS)
(24 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
9 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q9VD64 (/IDA) Q9VD64 (/IDA) Q9VD64 (/IDA)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
7 Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
7 Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q57XJ5 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
5 P36405 (/TAS) P36405 (/TAS) P36405 (/TAS) P36405 (/TAS) P36405 (/TAS)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
5 P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA) P36405 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P36405 (/HDA) P36405 (/HDA) P36405 (/HDA) P36405 (/HDA) P36405 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 E9ADU4 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
3 Q9WUL7 (/ISO) Q9WUL7 (/ISO) Q9WUL7 (/ISO)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
3 Q9WUL7 (/IDA) Q9WUL7 (/IDA) Q9WUL7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 E9ADU4 (/ISO)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
1 E9ADU4 (/ISO)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
1 E9ADU4 (/ISO)
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