The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 201: Glycine betaine/L-proline ABC transporter ATP-bind...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
|
91 |
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
(81 more) |
Osmosensor activity GO:0005034
Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.
|
79 |
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
(69 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
79 |
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
P14175 (/IPI)
(69 more) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
79 |
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
(69 more) |
ATPase-coupled quaternary ammonium compound transmembrane transporting activity GO:0015418
Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in).
|
26 |
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
(16 more) |
ATPase-coupled glycine betaine transporter activity GO:0031459
Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).
|
26 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(16 more) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
22 |
Q5LKZ7 (/ISS)
Q5LQP5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
(12 more) |
ATPase-coupled transmembrane transporter activity GO:0042626
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
|
22 |
Q5LKZ7 (/ISS)
Q5LUC2 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
(12 more) |
Carnitine transmembrane transporter activity GO:0015226
Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
21 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(11 more) |
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
|
20 |
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
(10 more) |
ATPase-coupled quaternary ammonium compound transmembrane transporting activity GO:0015418
Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in).
|
17 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(7 more) |
ATPase-coupled sulfate transmembrane transporter activity GO:0015419
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).
|
12 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(2 more) |
ATPase-coupled choline transmembrane transporter activity GO:0033266
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.
|
12 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(2 more) |
Sulfur compound transmembrane transporter activity GO:1901682
Enables the transfer of a sulfur compound from one side of a membrane to the other.
|
12 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(2 more) |
Nucleotide binding GO:0000166
Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
|
5 | Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) |
Carnitine transmembrane transporter activity GO:0015226
Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
5 | Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) |
ATPase-coupled choline transmembrane transporter activity GO:0033266
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.
|
5 | Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) Q9HXC2 (/ISS) |
Fibronectin binding GO:0001968
Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
|
2 | F9UNY1 (/IPI) F9UNY1 (/IPI) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
105 |
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
(95 more) |
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
82 |
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
P17328 (/IDA)
(72 more) |
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
|
79 |
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
P14175 (/IDA)
(69 more) |
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
|
79 |
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
P14175 (/IEP)
(69 more) |
Glycine betaine transport GO:0031460
The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
79 |
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
P14175 (/TAS)
(69 more) |
Quaternary ammonium group transport GO:0015697
The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
|
25 |
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
A0A1Q4LZ40 (/ISS)
(15 more) |
Amine transport GO:0015837
The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
20 |
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
(10 more) |
Amino-acid betaine transport GO:0015838
The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
17 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(7 more) |
Choline transport GO:0015871
The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
|
12 |
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
Q9HTI8 (/IMP)
(2 more) |
Glycine betaine catabolic process GO:0031457
The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.
|
12 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(2 more) |
Choline catabolic process GO:0042426
The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
|
12 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(2 more) |
Carnitine transmembrane transport GO:1902603
The directed movement of carnitine across a membrane.
|
12 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(2 more) |
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
9 | Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) |
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
9 | Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) |
Carnitine transport GO:0015879
The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
|
9 | Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) Q9RR46 (/IDA) |
Cellular hyperosmotic salinity response GO:0071475
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
5 | Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) Q9HXC2 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
|
79 |
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
P14175 (/ISM)
(69 more) |
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
20 |
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
(10 more) |
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
|
20 |
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
Q87WH5 (/ISS)
(10 more) |
ATP-binding cassette (ABC) transporter complex GO:0043190
A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
|
17 |
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
Q9HTI8 (/IDA)
(7 more) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | F9UNY1 (/IDA) F9UNY1 (/IDA) |