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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: Amino acid ABC transporter ATP-binding component

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
ABC-type polar-amino-acid transporter. [EC: 7.4.2.1]
ATP + H(2)O + polar amino acid-[polar amino acid-binding protein](Side 1) = ADP + phosphate + polar amino acid(Side 2) + [polar amino acid-binding protein](Side 1).
  • An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.
  • The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein and mediates the import of polar amino acids.
  • This entry comprises bacterial enzymes that import His, Arg, Lys, Glu, Gln, Asp, ornithine, octopine and nopaline.
  • Formerly EC 3.6.3.21.
 17689 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84 A0A023YT84
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