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CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 176: bifunctional heparan sulfate N-deacetylase/N-sulfo...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
[Heparan sulfate]-glucosamine N-sulfotransferase. [EC: 2.8.2.8]
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.
  • The enzyme also catalyzes the sulfation of chondroitin 4-sulfate and dermatan sulfate, but to a much more limited extent.
  • Formerly EC 2.8.2.12.
 19 A0A1L8GR65 A0A1L8GR65 E1JID8 E1JID8 O95803 O97583 P52848 P52849 P52850 Q02353
(9 more...)