The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1633: Thymidylate kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
11 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA)
(1 more)
Nucleoside diphosphate kinase activity GO:0004550
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
3 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA)
Nucleoside diphosphate kinase activity GO:0004550
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
3 P00572 (/IMP) P00572 (/IMP) P00572 (/IMP)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
3 P00572 (/IGI) P00572 (/IGI) P00572 (/IGI)
Thymidylate kinase activity GO:0004798
Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
3 P00572 (/IMP) P00572 (/IMP) P00572 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P00572 (/IPI) P00572 (/IPI) P00572 (/IPI)
Uridylate kinase activity GO:0009041
Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.
3 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DUDP biosynthetic process GO:0006227
The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).
11 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA)
(1 more)
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
11 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA) Q8I4S1 (/IDA)
(1 more)
Nucleoside diphosphate phosphorylation GO:0006165
The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
3 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA)
Nucleoside diphosphate phosphorylation GO:0006165
The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
3 P00572 (/IMP) P00572 (/IMP) P00572 (/IMP)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
3 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
3 P00572 (/IGI) P00572 (/IGI) P00572 (/IGI)
DTDP biosynthetic process GO:0006233
The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
3 P00572 (/IMP) P00572 (/IMP) P00572 (/IMP)
DTTP biosynthetic process GO:0006235
The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
3 P00572 (/IMP) P00572 (/IMP) P00572 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P00572 (/IDA) P00572 (/IDA) P00572 (/IDA)
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