The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 137: Replication-associated recombination protein A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q91XU0 (/IPI) Q96S55 (/IPI) Q96S55 (/IPI)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
2 Q96S55 (/IMP) Q96S55 (/IMP)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
2 Q8CG07 (/ISS) Q91XU0 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q96S55 (/IPI) Q96S55 (/IPI)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
1 Q91XU0 (/ISO)
Single-stranded DNA helicase activity GO:0017116
Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.
1 O13984 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q91XU0 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-dependent DNA replication GO:0006261
A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
79 P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI)
(69 more)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
79 P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI) P0AAZ4 (/IGI)
(69 more)
DNA synthesis involved in DNA repair GO:0000731
Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.
3 O13984 (/ISS) Q8CG07 (/ISS) Q91XU0 (/ISS)
DNA synthesis involved in DNA repair GO:0000731
Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.
2 Q96S55 (/IDA) Q96S55 (/IDA)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
2 Q96S55 (/IDA) Q96S55 (/IDA)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
2 Q8CG07 (/ISS) Q91XU0 (/ISS)
DNA synthesis involved in DNA repair GO:0000731
Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.
1 Q91XU0 (/ISO)
Regulation of DNA-dependent DNA replication initiation GO:0030174
Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
1 Q91XU0 (/ISO)
Okazaki fragment processing involved in mitotic DNA replication GO:1903461
Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.
1 O13984 (/ISO)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Replisome GO:0030894
A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
79 P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA) P0AAZ4 (/IDA)
(69 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q91XU0 (/IDA) Q96S55 (/IDA) Q96S55 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q8CG07 (/ISS) Q96S55 (/ISS) Q96S55 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O13984 (/ISO) Q91XU0 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q96S55 (/HDA) Q96S55 (/HDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 Q96S55 (/IDA) Q96S55 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q91XU0 (/ISO)
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