The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 106: Adenylate kinase mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 27 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
135 P07170 (/IDA) P07170 (/IDA) P07170 (/IDA) P27144 (/IDA) P27144 (/IDA) P29410 (/IDA) P29411 (/IDA) P33075 (/IDA) P69441 (/IDA) P69441 (/IDA)
(125 more)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
128 P07170 (/IMP) P07170 (/IMP) P07170 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP)
(118 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
128 P27144 (/IPI) P27144 (/IPI) P69441 (/IPI) P69441 (/IPI) P69441 (/IPI) P69441 (/IPI) P69441 (/IPI) P69441 (/IPI) P69441 (/IPI) P69441 (/IPI)
(118 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
124 P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA)
(114 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
124 P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA)
(114 more)
AMP binding GO:0016208
Interacting selectively and non-covalently with AMP, adenosine monophosphate.
124 P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA)
(114 more)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
63 Q08479 (/ISS) Q08479 (/ISS) Q08479 (/ISS) Q08479 (/ISS) Q08480 (/ISS) Q08480 (/ISS) Q08480 (/ISS) Q08480 (/ISS) Q08480 (/ISS) Q08480 (/ISS)
(53 more)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
11 Q08479 (/IEP) Q08479 (/IEP) Q08479 (/IEP) Q08479 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP)
(1 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
11 Q08479 (/IEP) Q08479 (/IEP) Q08479 (/IEP) Q08479 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP)
(1 more)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
9 P29410 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS)
Nucleoside diphosphate kinase activity GO:0004550
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
9 Q0VCP1 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q9WUR9 (/ISS) Q9WUR9 (/ISS) Q9WUS0 (/ISS)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
8 P54819 (/EXP) P54819 (/EXP) P54819 (/EXP) P54819 (/EXP) P54819 (/EXP) P54819 (/EXP) P54819 (/EXP) P54819 (/EXP)
Nucleoside triphosphate adenylate kinase activity GO:0046899
Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.
6 P26364 (/IDA) P26364 (/IDA) P27144 (/IDA) P27144 (/IDA) Q9UIJ7 (/IDA) Q9UIJ7 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
3 O82514 (/IDA) O82514 (/IDA) Q9FK35 (/IDA)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
2 Q9WTP6 (/ISO) Q9WTP7 (/ISO)
Nucleoside diphosphate kinase activity GO:0004550
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
2 P27144 (/IDA) P27144 (/IDA)
Nucleoside diphosphate kinase activity GO:0004550
Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
2 Q9WUR9 (/ISO) Q9WUR9 (/ISO)
Nucleoside triphosphate adenylate kinase activity GO:0046899
Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.
2 Q9UIJ7 (/EXP) Q9UIJ7 (/EXP)
Nucleoside monophosphate kinase activity GO:0050145
Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.
2 P27144 (/TAS) P27144 (/TAS)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
1 P33075 (/IGI)
Adenylate kinase activity GO:0004017
Catalysis of the reaction: ATP + AMP = 2 ADP.
1 Q5B2V8 (/RCA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 P33075 (/ISM)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P29411 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9WTP7 (/ISO)
Nucleoside triphosphate adenylate kinase activity GO:0046899
Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.
1 Q9WTP7 (/ISO)
Nucleoside triphosphate adenylate kinase activity GO:0046899
Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.
1 Q9VGU6 (/ISS)
(deoxy)adenylate kinase activity GO:0047506
Catalysis of the reaction: ATP + dAMP = ADP + dADP.
1 Q5B2V8 (/RCA)

There are 70 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ADP biosynthetic process GO:0006172
The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
124 P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP)
(114 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
124 P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP)
(114 more)
Phospholipid biosynthetic process GO:0008654
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
124 P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP)
(114 more)
Purine ribonucleotide interconversion GO:0015951
The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.
124 P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP)
(114 more)
RNA biosynthetic process GO:0032774
The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
124 P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP) P69441 (/IMP)
(114 more)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
50 Q71WG7 (/ISS) Q71WG7 (/ISS) Q71WG7 (/ISS) Q71WG7 (/ISS) Q71WG7 (/ISS) Q71WG7 (/ISS) Q749A8 (/ISS) Q749A8 (/ISS) Q81VQ9 (/ISS) Q81VQ9 (/ISS)
(40 more)
Purine nucleotide metabolic process GO:0006163
The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
11 Q08479 (/IEP) Q08479 (/IEP) Q08479 (/IEP) Q08479 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP) Q08480 (/IEP)
(1 more)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
10 P27144 (/TAS) P27144 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS)
Regulation of oxidative phosphorylation GO:0002082
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
9 Q0VCP1 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q9WUR9 (/ISS) Q9WUR9 (/ISS) Q9WUS0 (/ISS)
Nucleoside diphosphate phosphorylation GO:0006165
The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
9 Q0VCP1 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q9WUR9 (/ISS) Q9WUR9 (/ISS) Q9WUS0 (/ISS)
Nucleoside triphosphate biosynthetic process GO:0009142
The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
9 Q0VCP1 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q9WUR9 (/ISS) Q9WUR9 (/ISS) Q9WUS0 (/ISS)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
9 Q0VCP1 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q9WUR9 (/ISS) Q9WUR9 (/ISS) Q9WUS0 (/ISS)
Regulation of ATP biosynthetic process GO:2001169
Any process that modulates the frequency, rate or extent of ATP biosynthetic process.
9 Q0VCP1 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q5R421 (/ISS) Q9WUR9 (/ISS) Q9WUR9 (/ISS) Q9WUS0 (/ISS)
ADP biosynthetic process GO:0006172
The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
6 P07170 (/IDA) P07170 (/IDA) P07170 (/IDA) P29410 (/IDA) P29411 (/IDA) P33075 (/IDA)
AMP metabolic process GO:0046033
The chemical reactions and pathways involving AMP, adenosine monophosphate.
5 P27144 (/IDA) P27144 (/IDA) P29410 (/IDA) Q9UIJ7 (/IDA) Q9UIJ7 (/IDA)
AMP metabolic process GO:0046033
The chemical reactions and pathways involving AMP, adenosine monophosphate.
4 Q9WTP6 (/ISO) Q9WTP7 (/ISO) Q9WUR9 (/ISO) Q9WUR9 (/ISO)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
4 P27144 (/IDA) P27144 (/IDA) P29410 (/IDA) P29411 (/IDA)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
4 Q9WTP6 (/ISO) Q9WTP7 (/ISO) Q9WUR9 (/ISO) Q9WUR9 (/ISO)
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
4 P27144 (/IDA) P27144 (/IDA) Q9UIJ7 (/IDA) Q9UIJ7 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
3 P29410 (/IEP) P29411 (/IEP) Q9WUS0 (/IEP)
DNA replication initiation GO:0006270
The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.
3 P07170 (/IMP) P07170 (/IMP) P07170 (/IMP)
Nucleotide metabolic process GO:0009117
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
3 P07170 (/IMP) P07170 (/IMP) P07170 (/IMP)
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
3 A8KBS5 (/IMP) F1R4S7 (/IMP) Q7T333 (/IMP)
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
3 Q9WTP7 (/ISO) Q9WUR9 (/ISO) Q9WUR9 (/ISO)
Myeloid cell development GO:0061515
The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.
3 A8KBS5 (/IMP) F1R4S7 (/IMP) Q7T333 (/IMP)
Regulation of oxidative phosphorylation GO:0002082
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2 P27144 (/IMP) P27144 (/IMP)
Regulation of oxidative phosphorylation GO:0002082
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2 Q9WUR9 (/ISO) Q9WUR9 (/ISO)
Nucleoside diphosphate phosphorylation GO:0006165
The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
2 P27144 (/IDA) P27144 (/IDA)
Nucleoside diphosphate phosphorylation GO:0006165
The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
2 Q9WUR9 (/ISO) Q9WUR9 (/ISO)
ADP biosynthetic process GO:0006172
The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
2 Q9WTP6 (/ISO) Q9WTP7 (/ISO)
ADP biosynthetic process GO:0006172
The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
2 Q9U915 (/ISS) Q9VGU6 (/ISS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 P29410 (/IEP) Q9WUS0 (/IEP)
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
2 Q9UIJ7 (/TAS) Q9UIJ7 (/TAS)
Nucleotide metabolic process GO:0009117
The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
2 P26364 (/IDA) P26364 (/IDA)
Nucleoside triphosphate biosynthetic process GO:0009142
The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
2 P27144 (/IDA) P27144 (/IDA)
Nucleoside triphosphate biosynthetic process GO:0009142
The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
2 Q9WUR9 (/ISO) Q9WUR9 (/ISO)
ITP metabolic process GO:0046041
The chemical reactions and pathways involving ITP, inosine triphosphate.
2 Q9UIJ7 (/IDA) Q9UIJ7 (/IDA)
UTP metabolic process GO:0046051
The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.
2 Q9UIJ7 (/IDA) Q9UIJ7 (/IDA)
DATP metabolic process GO:0046060
The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
2 P29410 (/IDA) P29411 (/IDA)
DATP metabolic process GO:0046060
The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
2 Q9WTP6 (/ISO) Q9WTP7 (/ISO)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 O82514 (/IEP) O82514 (/IEP)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 P27144 (/IMP) P27144 (/IMP)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 Q9WUR9 (/ISO) Q9WUR9 (/ISO)
Regulation of ATP biosynthetic process GO:2001169
Any process that modulates the frequency, rate or extent of ATP biosynthetic process.
2 P27144 (/IMP) P27144 (/IMP)
Regulation of ATP biosynthetic process GO:2001169
Any process that modulates the frequency, rate or extent of ATP biosynthetic process.
2 Q9WUR9 (/ISO) Q9WUR9 (/ISO)
Hematopoietic progenitor cell differentiation GO:0002244
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
1 Q1L8L9 (/IMP)
Leukocyte differentiation GO:0002521
The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
1 Q1L8L9 (/IMP)
Oxidative phosphorylation GO:0006119
The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
1 P29410 (/IEP)
Purine ribonucleoside salvage GO:0006166
Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
1 Q54QJ9 (/ISS)
ADP biosynthetic process GO:0006172
The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
1 P33075 (/IGI)
AMP phosphorylation GO:0006756
The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.
1 P29411 (/IDA)
AMP phosphorylation GO:0006756
The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.
1 Q9WTP7 (/ISO)
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
1 P29411 (/IEP)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
1 Q38BZ2 (/TAS)
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
1 I1XB05 (/IMP)
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
1 P29411 (/IEP)
Olfactory bulb development GO:0021772
The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.
1 P29411 (/IEP)
Hemocyte proliferation GO:0035172
The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
1 I1XB05 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q9WUS0 (/IEP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 P29411 (/IEP)
Nucleotide salvage GO:0043173
Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.
1 Q5B2V8 (/RCA)
ITP metabolic process GO:0046041
The chemical reactions and pathways involving ITP, inosine triphosphate.
1 Q9WTP7 (/ISO)
UTP metabolic process GO:0046051
The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.
1 Q9WTP7 (/ISO)
Adenine metabolic process GO:0046083
The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
1 P29410 (/TAS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P29411 (/IDA)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9WTP7 (/ISO)
Hematopoietic stem cell differentiation GO:0060218
The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
1 Q1L8L9 (/IMP)
Negative regulation of protein kinase C signaling GO:0090038
Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
1 P34346 (/IGI)
Response to thyroid hormone GO:0097066
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
1 P29410 (/IEP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 P34346 (/IGI)

There are 32 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
125 P29410 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA) P69441 (/IDA)
(115 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
14 D3DQ64 (/IDA) D3DQ64 (/IDA) D3DQ64 (/IDA) D3DQ64 (/IDA) D3DQ64 (/IDA) O82514 (/IDA) O82514 (/IDA) P27144 (/IDA) P27144 (/IDA) P29410 (/IDA)
(4 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
11 P07170 (/HDA) P07170 (/HDA) P07170 (/HDA) P26364 (/HDA) P26364 (/HDA) Q9U915 (/HDA) Q9VGU6 (/HDA) Q9WTP6 (/HDA) Q9WTP7 (/HDA) Q9WUR9 (/HDA)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
10 P08166 (/ISS) P08166 (/ISS) P08760 (/ISS) P08760 (/ISS) P29411 (/ISS) Q7Z531 (/ISS) Q95J94 (/ISS) Q9D8W6 (/ISS) Q9UIJ7 (/ISS) Q9UIJ7 (/ISS)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
8 P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS) P54819 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
8 P54819 (/HDA) P54819 (/HDA) P54819 (/HDA) P54819 (/HDA) P54819 (/HDA) P54819 (/HDA) P54819 (/HDA) P54819 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
6 P26364 (/IDA) P26364 (/IDA) P29411 (/IDA) Q9WTP7 (/IDA) Q9WUR9 (/IDA) Q9WUR9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P07170 (/IDA) P07170 (/IDA) P07170 (/IDA) P29410 (/IDA) Q38BZ2 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
5 P07170 (/IDA) P07170 (/IDA) P07170 (/IDA) P29410 (/IDA) P29411 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
5 P27144 (/ISS) P27144 (/ISS) Q9UIJ7 (/ISS) Q9UIJ7 (/ISS) Q9VGU6 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q9WTP6 (/ISO) Q9WTP7 (/ISO) Q9WUR9 (/ISO) Q9WUR9 (/ISO)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
4 P27144 (/TAS) P27144 (/TAS) Q9UIJ7 (/TAS) Q9UIJ7 (/TAS)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
3 P33075 (/ISO) Q9WTP6 (/ISO) Q9WTP7 (/ISO)
Vacuolar membrane GO:0005774
The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
3 O82514 (/IDA) O82514 (/IDA) Q9FK35 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q4Q3J7 (/ISO) Q9WTP6 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P26364 (/IDA) P26364 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P08166 (/ISS) P08166 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P33075 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P29410 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9WTP6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q54QJ9 (/ISS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q9WTP6 (/HDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 Q9U915 (/ISS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q9WTP7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P33075 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9WTP6 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q38BZ2 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q4Q3J7 (/ISO)
Sperm flagellum GO:0036126
A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
1 Q9WTP6 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q38BZ2 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4Q3J7 (/ISO)
Sperm mitochondrial sheath GO:0097226
The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.
1 Q9WTP6 (/IDA)
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